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Figure 8 | BMC Genomics

Figure 8

From: Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays

Figure 8

Complex losses and gains in the q-arm of Chr:16 of sample C111. The figure shows the LR from the 500 K (top) and 19 K BAC (bottom) arrays with the genomic scale (x-axis) indicating the SNP position or the center point of the BAC clone. The status of the CN changes is more clearly resolved with the 500 K arrays than with the BAC array, particularly for two sizeable regions of loss (between 45 Mb-54 Mb and 59 Mb – 63 Mb). Furthermore, CGH does not clearly detect a loss at 20.88 – 23.36 Mb and a copy neutral region within a deletion at 77.14 – 77.54 Mb (arrows).

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BMC Genomics

ISSN: 1471-2164

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