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Table 3 Genes modulated specifically at day 14

From: Disturbances in metabolic, transport and structural genes in experimental colonic inflammation in the rat: a longitudinal genomic analysis

Gene symbol

Gene name

FC

SEM

Tbx15_predicted

T-box 15 (predicted)

8.00

1.74

Trhr

Thyrotropin releasing hormone receptor

5.67

1.26

Ppp3cc

Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma)

5.07

3.34

Eif2ak3

Eukaryotic translation initiation factor 2 alpha kinase 3

4.92

2.25

Hrh3

Histamine receptor H3

4.35

1.34

Klf15

Kruppel-like factor 15

3.58

0.39

Gldc_predicted

Glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P) (predicted)

3.40

1.49

Trdn

Triadin

3.18

0.53

Galr1

Galanin receptor 1

3.15

0.04

Mlana_predicted

Melan-A (predicted)

2.30

0.47

Cma1

Chymase 1, mast cell

2.15

0.30

Trerf1_predicted

Transcriptional regulating factor 1 (predicted)

1.91

0.10

Serbp1

Serpine1 mRNA binding protein 1

1.85

0.22

Ltb4dh

Leukotriene B4 12-hydroxydehydrogenase

1.78

0.24

Fgf1

Fibroblast growth factor 1

1.75

0.28

Ace

Angiotensin 1 converting enzyme

1.72

0.33

Eif4a1

Eukaryotic translation initiation factor 4A1

1.68

0.38

Adar

Adenosine deaminase, RNA-specific

1.59

0.12

Ddb1

Damage-specific DNA binding protein 1

1.57

0.05

Mbnl

Muscleblind-like 1 (Drosophila)

1.52

0.10

Lzts1

Leucine zipper, putative tumour suppressor 1

1.52

0.16

Hmga1

High mobility group AT-hook 1

1.51

0.13

Apoa5

Apolipoprotein A-V

0.08

0.01

Strn

Striatin, calmodulin binding protein

0.09

0.05

Olfm3

Olfactomedin 3

0.09

0.01

Cdc2l5

Cell division cycle 2-like 5 (cholinesterase-related cell division controller)

0.11

0.03

Prom2

Prominin 2

0.11

0.02

Snag1_predicted

Sorting nexin associated golgi protein 1 (predicted)

0.11

0.03

Serpina3m

Serine (or cysteine) proteinase inhibitor, clade A, member 3M

0.12

0.02

Ank1_predicted

Ankyrin 1, erythroid (predicted)

0.13

0.00

Hist1h1t

Histone 1, h1t

0.15

0.02

Imp1

Insulin-like growth factor 2, binding protein 1

0.15

0.03

Cacng7

Calcium channel, voltage-dependent, gamma subunit 7

0.16

0.05

Rbm9_predicted

RNA binding motif protein 9 (predicted)

0.19

0.03

Drp2

Dystrophin-related protein 2 A-form splice variant

0.20

0.03

Eif4g1

Eukaryotic translation initiation factor 4 gamma, 1

0.20

0.01

Apob

Apolipoprotein B

0.21

0.07

Wt1

Wilms tumor 1

0.23

0.02

Pqlc2_predicted

PQ loop repeat containing 2 (predicted)

0.25

0.07

Cnr1

Cannabinoid receptor 1 (brain)

0.25

0.02

Lmo3

LIM domain only 3

0.26

0.03

Bai3_predicted

Brain-specific angiogenesis inhibitor 3 (predicted)

0.28

0.04

Sp3

Sp3 transcription factor

0.31

0.02

Apba1

Amyloid beta (A4) precursor protein-binding, family A, member 1

0.32

0.03

Kcnc3

Potassium voltage gated channel, Shaw-related subfamily, member 3

0.44

0.06

Actc1

Actin alpha cardiac 1

0.45

0.06

Wnt11

Wingless-type MMTV integration site family, member 11

0.47

0.09

Il2

Interleukin 2

0.50

0.08

Galnt2_predicted

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (predicted)

0.57

0.02

Nrg2

Neuregulin 2

0.60

0.04

Cspg4

Chondroitin sulphate proteoglycan 4

0.60

0.02

Enth

Enthoprotin

0.61

0.03

Zfp503_predicted

Zinc finger protein 503 (predicted)

0.66

0.02

Rbm3

RNA binding motif (RNP1, RRM) protein 3

0.66

0.02

Mpp5_predicted

Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) (predicted)

0.66

0.01

Prg1

Plasticity related gene 1

0.67

0.02

Csnk1d

Casein kinase 1, delta

0.67

0.06

  1. Only annotated genes with a 50% or higher fold change are included. In all cases the FC at days 2 – 7 was not significantly different from the control (significance at P > 0.10 to exclude transcripts that were not specifically upregulated or downregulated at only day 14).