Genomic analysis of the chromosome 15q11-q13 Prader-Willi syndrome region and characterization of transcripts for GOLGA8E and WHCD1L1 from the proximal breakpoint region

Table 2 The genome distribution of Golgin subfamily genes in human and mouse

Table	Gene symbol	accession No.	map position	genomic location	aa.	Iden%
Human	GOLGA8E*	NM_001012423	15q11	20986537–20999858	430	100
	GOLGA8A*	NM_015003	15q14	32458564–32487180	460	72
	GOLGA8B	NM_001023567	15q14	32604594–32613203	459	72
	GOLGA8G*	NM_01012420	15q13	26297495–26577158	260	97
	GOLGA	NM_018652	15q24.	70734092–70746791	693	49
	GOLGA6*	NM_010103840	15q26	72149251–72161944	693	48
	GOLGA1	NM_002077	9q33	126680450–126743178	767	22
	GOLGA2	NM_004486	9q34	130057930–130078089	430	47
	GOLGA3	AF485338	12q24	131859669–131908790	1498	22
	GOLGA4*	NM_002078	3p22	37259742–37383245	2230	25
	GOLGA5	NM_005113	14q32	92330403–92376057	731	23
	GOLGA7	NM_001002296	8p11	41467330–41487654	137	N
	GOLGB1	NM_004487	3q13	122865640–122951292	3259	24
	GORASP2	NM_15530	2q31	171493957–171531885	452	N
	GOLGA2L1	NM_017600	1223	99074326–99091202	144	36
	AF332229¶	AF332229	Yq11	24765503–24770366	184	45
Mouse	Golga1	NM_029793	2qB	126680478–126740968	758	20
	Golga3	NM_008146	59F	131859857–131908959	1447	25
	Golga4	NM_018748	9qF3	37259816–37383239	2238	24
	Golga5	NM_001033065	129E	92333536–92375541	729	25
	Golga7	NM_001042484	8qA2	41467233–41487467	137	N

* Indicates multiple isoforms for this protein but only one is shown in table, # the nucleotide position is referred to UCSC browser human genome build 36.1 and mouse genome build 36. aa, amino acid. Iden% of AA is the percentage of identity of amino acids for each gene deduced from BLAST 2 program when against to GOLGA8E. The 'N' indicates no significant sequence identity. ¶AF33229 is referred as Golgi autoantigen, golgin subfamily a2-like protein.

ISSN: 1471-2164