Table 4 Overview of hepatic transcripts exhibiting differential expression between the two genotypes (F vs L)1
Statistical analysis | ANOVA (p < 0.01) | SAM FDR ≤ 0.15 | ANOVA∩SAM |
|---|---|---|---|
Total | 154 | 77 | 70 |
F > L | 90 | 65 | 58 |
F < L | 64 | 12 | 12 |
Transcripts with known biological function | 127 | 64 | 58 |
Biological function | |||
Metabolism | 47 (37.0%) | 30 (46.7%) | 27 (46.6%) |
Lipid | (4.67%) | 2 (3.1%) | 2 (3.4%) |
Precursor metabolites and energy | 7 (5.5%) | 6 (9.4%) | 5 (8.6%) |
Carbohydrate | 2 (1.6%) | 1 (1.6%) | 1 (1.7%) |
Amino acid and derivative | 9 (7.1%) | 6 (9.4%) | 5 (8.6%) |
Protein folding/synthesis/breakdown | 11 (8.7%) | 6 (9.4%) | 5 (8.6%) |
Xenobiotic and oxidant | 7 (5.5%) | 6 (9.4%) | 6 (10.3%) |
Purine and pyrimidine | 3 (2.4%) | 3 (4.7%) | 2 (3.4%) |
Iron | 2 (1.6%) | 1 (1.6%) | 1 (1.7%) |
Transcription/translation | 19 (15.0%) | 3 (4.7%) | 2 (3.4%) |
Immune response | 7 (5.5%) | 5 (7.8%) | 5 (8.6%) |
Trafficking | 11 (8.7%) | 5 (7.8%) | 5 (8.6%) |
Signal transduction | 7 (5.5%) | 3 (4.7%) | 3 (5.2%) |
Cell cycle | 9 (7.1%) | 5 (7.8%) | 4 (6.9%) |
Extracellular matrix and structural components | 9 (7.1%) | 3 (4.7%) | 2 (3.4%) |
Others | 18 (14.2%) | 10 (15.6%) | 10 (17.2%) |