Table 4 Genes downregulated by TSA treatment in HEPG2 cells (representative genes from total of 2975 genes at 2-fold level of expression)
From: Histone deacetylase inhibitors: A new mode for inhibition of cholesterol metabolism
Treatment type | EtOH | TSA | Â | Â | |||
|---|---|---|---|---|---|---|---|
Systematic | FC | Norm | SE | Norm | SE | Gene | GB Acc |
205890_s_at | -30.7 | 0.975 | 0.05 | 0.032 | 0.02 | UBD | NM_006398 |
220437_at | -12.6 | 0.976 | 0.08 | 0.078 | 0.06 | LOC55908 | NM_018687 |
223493_at | -11.5 | 1.056 | 0.07 | 0.092 | 0.06 | FBXO4 | AF129534 |
226388_at | -11.4 | 1.015 | 0.06 | 0.089 | 0.03 | TCEA3 | AI675780 |
202589_at | -9.6 | 1.07 | 0.09 | 0.11 | 0.04 | TYMS | NM_001071 |
203979_at | -8.7 | 1.007 | 0.08 | 0.115 | 0.05 | CYP27A1 | NM_000784 |
226216_at | -7.2 | 0.887 | 0.11 | 0.123 | 0.06 | INSR | W84556 |
209608_s_at | -6.3 | 1.034 | 0.06 | 0.163 | 0.03 | ACAT2 | BC000408 |
203924_at | -6.2 | 0.974 | 0.05 | 0.158 | 0.04 | GSTA2 | NM_000846 |
205208_at | -6.9 | 1.03 | 0.08 | 0.15 | 0.06 | FTHFD | NM_012190 |
219366_at | -5.6 | 0.954 | 0.14 | 0.169 | 0.06 | AVEN | NM_020371 |
205820_s_at | -5.3 | 1.02 | 0.06 | 0.19 | 0.04 | APOC3 | NM_000040 |
209546_s_at | -5.2 | 0.99 | 0.06 | 0.19 | 0.07 | APOL1 | AF323540 |
224243_at | -4.6 | 1.10 | 0.12 | 0.24 | 0.05 | APOA5; RAP3 | AF202889 |
200789_at | -4.0 | 0.96 | 0.11 | 0.24 | 0.03 | ECH1; HPXEL | NM_001398 |
221750_at | -3.8 | 0.99 | 0.05 | 0.26 | 0.04 | HMGCS1 | BG035985 |
202068_s_at | -3.6 | 1.00 | 0.06 | 0.28 | 0.04 | LDLR; FH; FHC | NM_000527 |
225012_at | -3.1 | 0.99 | 0.09 | 0.32 | 0.04 | HDLBP | BE378479 |
213577_at | -3.1 | 1.03 | 0.09 | 0.34 | 0.05 | SQLE | AA639705 |
202067_s_at | -2.9 | 0.88 | 0.12 | 0.30 | 0.16 | LDLR | AI861942 |
202502_at | -2.8 | 0.97 | 0.05 | 0.35 | 0.03 | ACADM; MCAD; | NM_000016 |
201248_s_at | -2.6 | 1.00 | 0.08 | 0.39 | 0.04 | SREBF2; SREBP2 | NM_004599 |
209218_at | -2.5 | 1.01 | 0.06 | 0.40 | 0.04 | SQLE | AF098865 |
222916_s_at | -2.3 | 0.92 | 0.12 | 0.40 | 0.06 | HDLBP | AF116718 |
201791_s_at | -2.2 | 0.99 | 0.07 | 0.45 | 0.04 | DHCR7; SLOS | NM_001360 |