Figure 5

DNA Microarray and ISH modules. By consulting a term of the ontology a pop-up frame allows the user to browse DNA microarray experiments present in the database, as shown in the upper panel. Experiments can be browsed using several parameters: chip design, hybridization platform and labelling. Once an experiment is selected, those genes showing expression appear in the lower list. Expression values can then be selected according to a lower threshold value and sent to the work list of the main interface for further consultation. The lower panel shows that Soleamold also allows for the storage, consultation and interpretation of ISH experiments. The figure shows the distinct browsing interfaces for this type of data. In the foreground, the original experimental pictures browsing interface shows steroidogenic acute regulatory (StAR) mRNA expression in Leydig cells, and its zoomed image. In the background, there is the automatically built, atlas image, of the same experiment showing the expression in Leydig cells as interpreted by the user at the insertion time.