Skip to main content

Table 3 The number of incongruent topologies detected by the Shimodaira-Hasegawa (SH) test.

From: Multiple genome alignment for identifying the core structure among moderately related microbial genomes

Bacillaceae

     
 

core

non-core

 

N

rejected

total

rejected

total

p-value

4

3 (3.5)

85

32 (14.0)

228

0.004573

5

11 (6.2)

176

38 (21.6)

176

2.170e-05

6

17 (5.4)

314

34 (29.6)

115

1.899e-10

7

32 (4.3)

739

9 (15.5)

58

0.001705

total

63 (4.8)

1314

113 (19.6)

577

<2.2e-16

Enterobacteriaceae

     
 

core

non-core

 

N

rejected

total

rejected

total

p-value

4

6 (5.0)

121

19 (17.1)

111

0.002496

5

12 (5.1)

235

21 (24.4)

86

2.784e-06

6

28 (5.7)

490

9 (34.6)

26

2.431e-05

7

45 (4.1)

1099

0 (0.0)

8

1

total

91 (4.7)

1945

49 (21.2)

231

6.409e-16

  1. The SH test was performed for all OGs (both core and non-core) that have a one-to-one correspondence using the TREE-PUZZLE program with the ML topology (or its subtree) of the concatenated core sequences (Figure 8A) as a reference tree, and the numbers of rejected (significantly incongruent) cases were compared between core and non-core classes using the Fisher's exact test. The first column (N) indicates effective number of genomes where genomes of closely related species were counted only once. The column "rejected" indicates the number of cases rejected by the SH test at a significance level of 0.05; the number in parentheses is the percentage of rejected cases. The last column indicates the p-value of a one-sided Fisher's exact test.