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Figure 1 | BMC Genomics

Figure 1

From: mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft

Figure 1

Characterization of cultured A549 and A549 ρ0 cells. (A) Growth rates of A549 and A549 ρ0 cells in culture are provided. Experiments were run in triplicate with error bars representing ± 1 standard deviation. Doubling times obtained from the fitted curves (N = N0ert) were 20.4 and 27.3 hours for parental A549 and A549 ρ0 cultures, respectively. (B) The oxygen consumption of A549 and A549 ρ0 cultured cells is provided. Where indicated, cells were treated with 1 μg/mL antimycin A, an inhibitor of the mitochondrial electron transport chain (ETC). Experiments were run in triplicate with error bars representing ± 1 standard deviation.

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BMC Genomics

ISSN: 1471-2164

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