Table 2 Analysis of over- and under-represented MIPS annotations terms for differentially-expressed gene set
MIPS FUNCTION | number of elements on the array | number of elements differentially expressed | number of elements expected to be differentially expressed | fold over or under represented | p-value | adjusted p-value |
|---|---|---|---|---|---|---|
SUBCELLULAR LOCALIZATION | 1263 | 3 | 50.25 | -16.75 | 0 | 0 |
PROTEIN FATE (folding, modification, destination) | 633 | 6 | 25.17 | -4.20 | 9.11E-07 | 1.64E-05 |
PROTEIN SYNTHESIS | 525 | 4 | 20.88 | -5.22 | 1.18E-06 | 2.12E-05 |
CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION MECHANISM | 741 | 9 | 29.47 | -3.27 | 2.26E-06 | 4.07E-05 |
ENERGY | 439 | 3 | 17.48 | -5.83 | 3.55E-06 | 6.38E-05 |
PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic) | 618 | 7 | 24.58 | -3.51 | 6.71E-06 | 1.21E-04 |
DEVELOPMENT (Systemic) | 261 | 1 | 10.39 | -10.39 | 2.67E-05 | 4.8E-04 |
CELL FATE | 256 | 2 | 10.19 | -5.09 | 3.79E-04 | 6.82E-04 |
INTERACTION WITH THE CELLULAR ENVIRONMENT | 146 | 2 | 5.79 | -2.90 | 0.02 | 0.37 |
BIOGENESIS OF CELLULAR COMPONENTS | 542 | 12 | 21.58 | -1.80 | 0.01 | 0.17 |
CELL CYCLE AND DNA PROCESSING | 289 | 7 | 11.49 | -1.64 | 0.06 | 1 |
TRANSCRIPTION | 726 | 24 | 28.87 | -1.20 | 0.17 | 1 |
CELL RESCUE, DEFENSE AND VIRULENCE | 577 | 21 | 22.977 | -1.09 | 0.33 | 1 |
CELLULAR TRANSPORT, TRANSPORT FACILITATION AND TRANSPORT ROUTES | 758 | 28 | 30.17 | -1.08 | 0.34 | 1 |
CLASSIFICATION NOT YET CLEAR-CUT | 1072 | 44 | 42.66 | 1.03 | 0.59 | 1 |
UNCLASSIFIED PROTEINS | 14494 | 711 | 565.43 | 1.26 | 1 | 1 |
METABOLISM | 1737 | 111 | 69.13 | 1.61 | 1 | 1 |
STORAGE PROTEIN | 30 | 4 | 1.20 | 3.34 | 0.97 | 1 |