Figure 6

Pyrethroid effects on branching and neurite length in primary cortical cell cultures. Changes in the total number neurite of branch points (A & D), total neurite length (B & E) and cell viability (C & F) in primary cortical cell cultures exposed to deltamethrin (A-C) or permethrin (D-F). n = 3 replicate experiments. Values for each end point are normalized to untreated controls (± standard error). Untreated control values are shown in white. The bold lines underneath each curve represent the range of estimated brain concentrations expected to occur during the in vivo exposures used in the present study (Mirfazaelian et al. 2006 and Tornero-Velez et al. 2007). Significance was determined using a One-way ANOVA, * = p < 0.10, ** = p < 0.05.