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Table 2 Probe sets identified as dose-responsive for deltamethrin.

From: Transcriptional response of rat frontal cortex following acute In Vivo exposure to the pyrethroid insecticides permethrin and deltamethrin

  

Linear Regression (SAM)

Isotonic Regression (PIR)

ANOVA

Affymetrix Probe Set I.D.

Gene Symbol

d i

p-value

q-value

M i

p-value

q-value

p-value

1371363_at

Gpd1**

5.63

0.0000

0.00

2.34

0.0000

0.24

0.0032

1388901_at

Fkbp51**

5.46

0.0000

0.00

2.21

0.0000

0.42

0.0051

1367577_at

Hsp27**

4.60

0.0001

0.00

1.90

0.0002

0.97

0.0195

1369560_at

Gpd1**

4.53

0.0001

0.00

1.91

0.0002

1.00

0.0134

1368064_a_at

Ddc**

-4.35

0.0001

0.14

-1.95

0.0002

1.00

0.0195

1391229_at

Camk1g**

4.22

0.0002

0.00

2.11

0.0000

0.51

0.0063

1380611_at

Fkbp51**

3.90

0.0004

0.11

1.62

0.0012

1.00

0.0276

1369303_at

Crh

3.62

0.0009

0.11

1.73

0.0006

1.00

0.0276

1388271_at

LOC689415

3.48

0.0013

0.19

1.44

0.0037

1.00

0.0300

1370989_at

Ret

3.38

0.0017

0.19

1.49

0.0028

1.00

0.0300

1370026_at

Cryab

3.28

0.0022

0.29

1.46

0.0032

1.00

0.0364

1374626_at

Lrg1

3.23

0.0025

0.33

1.45

0.0036

1.00

0.0323

1376709_at

Slc39a8

-3.07

0.0038

0.14

-1.49

0.0026

1.00

0.0364

1368650_at

Klf10

-3.07

0.0038

0.14

-1.30

0.0077

1.00

0.0356

1380329_at

Tmem10

-3.03

0.0041

0.14

-1.28

0.0086

1.00

0.0496

1372564_at

Ets2

3.03

0.0042

0.51

1.41

0.0045

1.00

0.0396

1389507_at

Nedd4l

2.97

0.0048

0.51

1.42

0.0043

1.00

0.0306

1375138_at

Timp3

2.92

0.0054

0.56

1.22

0.0134

1.00

0.0319

1370530_a_at

Pld1

-2.81

0.0071

0.14

-1.34

0.0062

1.00

0.0493

1385778_at

Siat7E

2.79

0.0075

1.15

1.38

0.0055

1.00

0.0276

1395986_at

Slit2

-2.78

0.0077

0.14

-1.27

0.0094

1.00

0.0419

1369973_at

Xdh

2.76

0.0080

1.15

1.18

0.0167

1.00

0.0472

1368438_at

Pde10a

2.70

0.0094

1.16

1.11

0.0255

1.00

0.0496

1387260_at

Klf4

-2.69

0.0096

0.14

-1.49

0.0026

1.00

0.0429

1372356_at

Usp54

2.69

0.0097

1.16

1.12

0.0240

1.00

0.0442

1371442_at

Hyou1

2.68

0.0099

1.16

1.03

0.0384

1.00

0.0467

1375296_at

LOC684097

2.66

0.0105

1.16

1.40

0.0047

1.00

0.0427

1398899_at

Polr2c

2.64

0.0110

1.16

1.67

0.0009

1.00

0.0195

1377518_at

Camk1g**

2.59

0.0123

1.16

1.29

0.0090

1.00

0.0315

1372090_at

Max

2.53

0.0143

1.16

1.31

0.0080

1.00

0.0306

1381557_at

Gna14

2.35

0.0216

1.16

1.29

0.0087

1.00

0.0442

1398373_at

B3galt3

2.29

0.0248

1.16

1.29

0.0091

1.00

0.0396

1372037_at

Pdlm7

2.18

0.0319

1.16

1.28

0.0098

1.00

0.0351

1382112_at

LOC682926

-2.16

0.0333

1.15

-1.26

0.0096

1.00

0.0344

1375752_at

Bves

-1.96

0.0519

1.15

-1.41

0.0042

1.00

0.0376

1370869_at

Bcat1

1.92

0.0561

1.16

1.28

0.0096

1.00

0.0345

1367706_at

Vdac1

1.74

0.0820

1.16

1.29

0.0090

1.00

0.0295

  1. ** = genes examined by qRT-PCR. Positive SAM d i or PIR M i scores denote upregulated probe sets. Negative SAM d i or PIR M i scores denote downregulated probe sets. A full list of probe sets altered by deltamethrin exposure, including predicted protein coding sequences and expressed sequence tags is given in Additional file 3.