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Figure 2 | BMC Genomics

Figure 2

From: Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2)

Figure 2

Identification of patterns among kinetically perturbed genes in YSK4425 using principal component analysis (PCA). (a) Eigenvector plots for principal components 1 and 2 – PC-1 (red) and PC-2 (blue) which represent the major patterns in differential expression profiles. PCA was performed on the 'difference profiles' between the two strains to find patterns in differential expression. (b) Fraction of variation accounted for by the first two and the rest of principal components. (c) Plot of PC-1 vs PC-2 identifies genes that have a high value along each of PC-1 and PC-2. Actinorhodin biosynthesis genes are shown as filled green triangles, while certain other interesting genes are also marked (red circles for high PC-1 and blue circles for high PC-2). The figure indicates that several functionally related genes, particularly phosphate and nitrogen metabolism related elements, and actinorhodin biosynthesis genes cluster together in various regions of the plot.

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