Network interaction map for luminal ER- specific genes. Interaction data based on physical interactions (solid lines) and transcriptional interactions (dashed lines). The nodes are colour coded to indicate relative strengths of expression of the gene within the cell population. Brighter reds indicate highest levels of expression. Darker reds indicate genes less strongly expressed (although still with enriched expression within the population compared to the other cell types). White nodes indicate interpolated genes used by the network mapping software to extend and link the network [see Additional file 12]. A) Whole interaction map. Box indicates Toll-like receptor module. B) Enlargement of Toll-like receptor interaction module.