Skip to main content

Table 11 Summary of Gene Ontology analysis results

From: Differential RelA- and RelB-dependent gene transcription in LTβR-stimulated mouse embryonic fibroblasts

Category/Subcategory Enriched biological processes Regulatory molecules downstream of LTβR, and their effects on the gene expression
Total wild-type A/CD
CCY
IR
BR
Molecules not assignable – up and downregulation
Cat I CCY RelA and RelB together – up and downregulation
Cat I/1 IR RelA and RelB together – upregulation
Cat I/2 CCY RelA and RelB together – downregulation
Cat II CCY RelB – up and downregulation
Cat II/1 Not investigated RelB – upregulation
Cat II/2 Not investigated RelB – downregulation
Cat III T
A/CD
IR
RelA – up and downregulation
Cat III/1 T
IR
RelA – upregulation
Cat III/2 ION
BR
RelA – downregulation
Cat IV IR
T
LY
RelA and RelB via redundant effects – up and downregulation
OR
Third pathway – up and downregulation
Cat IV/1 IR
T
RelA and RelB via redundant effects – upregulation
OR
Third pathway – upregulation
Cat IV/2 Not investigated RelA and RelB via redundant effects – downregulation
OR
Third pathway – downregulation
  1. Summary of GO analysis: categories/subcategories with their respective enriched biological processes and the assigned regulatory mechanisms are listed. A/CD, apoptosis/cell death; CCY, cell cycle; IR, immune related; BR, blood vessel development related; T, taxis, response to external/chemical stimulus; ION, ion homeostasis; LY, hematopoietic or lymphoid organ developmental processes. Since cat II/1, II/2 and cat IV/2 had only few genes (n = 13, 17 and 10, respectively) they were not investigated for GO terms.
\