Table 11 Summary of Gene Ontology analysis results
Category/Subcategory | Enriched biological processes | Regulatory molecules downstream of LTβR, and their effects on the gene expression |
|---|---|---|
Total wild-type | A/CD CCY IR BR | Molecules not assignable – up and downregulation |
Cat I | CCY | RelA and RelB together – up and downregulation |
Cat I/1 | IR | RelA and RelB together – upregulation |
Cat I/2 | CCY | RelA and RelB together – downregulation |
Cat II | CCY | RelB – up and downregulation |
Cat II/1 | Not investigated | RelB – upregulation |
Cat II/2 | Not investigated | RelB – downregulation |
Cat III | T A/CD IR | RelA – up and downregulation |
Cat III/1 | T IR | RelA – upregulation |
Cat III/2 | ION BR | RelA – downregulation |
Cat IV | IR T LY | RelA and RelB via redundant effects – up and downregulation OR Third pathway – up and downregulation |
Cat IV/1 | IR T | RelA and RelB via redundant effects – upregulation OR Third pathway – upregulation |
Cat IV/2 | Not investigated | RelA and RelB via redundant effects – downregulation OR Third pathway – downregulation |