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Figure 1 | BMC Genomics

Figure 1

From: Conservation and implications of eukaryote transcriptional regulatory regions across multiple species

Figure 1

Core TRRs analysis for yeast. (A) The average score of 1317 genes on chromosomes XIII-XVI with annotation "Verified" and with ORF regions of more than 400 bp from S. cerevisiae for each position in (-500, +400) (blue curve). The red curve is the same as the blue curve, but using genes on chromosomes I-XII with annotation "Verified" and with ORF regions of more than 400 bp from S. cerevisiae. The "0" in the x-axis indicates the initial ATG codon. The dashed curves are generated by plotting the mean TRR score of each position ± 1 standard deviations of each position. (B) ROC curves for HSL model in yeast. The x-axis represents the false positive (FP) rate; the y-axis represents the true positive (TP) rate. (C) The same as (A) except we aligned genes by their TSSs. The average score of genes on chromosomes XIII-XVI with annotation of TSSs from [23] (blue curve). The red curve is the same as the blue curve, but using genes on chromosomes I-XII. The "0" in the x-axis indicates the TSS. The dashed curves are generated by plotting the mean TRR score of each position ± 1 standard deviations of each position.

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