Figure 1

Examples for different cyst gradings in 36 day old male PKD/Mhm rats. At this age cyst grades of heterozygous (PKD/Mhm (cy/+)) affected kidneys are ranging between grade 3 (B) and 4(C), compared to a homozygous unaffected (healthy) kidney (A). Most of the animals are showing cyst grade 3. Hematoxylin/Eosin stained; Scale bar 250 μm.