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Table 1 Selection of significant up-regulated expression of cytokines, cytokine receptors, chemokines, chemokine receptors, regulatory or protective genes after allogeneic transplantation compared to control group.

From: Activation of counter-regulatory mechanisms in a rat renal acute rejection model

Fold change Probe set Description Gene symbol
Cytokines
121.2 1387711_at interleukin 10 Il10
84.1 1370790_at interferon gamma Ifng
41.6 1391384_at tumor necrosis factor (TNF superfamily, member 2) Tnf
15.4 1398256_at interleukin 1 beta Il1b
13.1 1368592_at interleukin 1 alpha Il1a
8.6 1369665_a_at interleukin 18 Il18
8.4 1368763_at interleukin 3 Il3
7.4 1369191_at interleukin 6 Il6
6.1 1369208_at interleukin 7 Il7
Cytokine receptors
17 1389092_at interleukin 2 receptor, gamma Il2rg
13.6 1387591_at interleukin 2 receptor, alpha chain Il2ra
11.8 1369697_at interleukin 8 receptor, beta Il8rb
10.1 1387394_at interleukin 2 receptor, beta chain Il2rb
3.5 1370728_at interleukin 13 receptor, alpha 1 Il13ra1
3 1386987_at interleukin 6 receptor Il6r
Chemokines
139.7 1382454_at chemokine (C-X-C motif) ligand 9 Cxcl9
122.8 1387831_at small inducible cytokine subfamily C, member 1 (lymphotactin) Xcl1
39.3 1387969_at chemokine (C-X-C motif) ligand 10 Cxcl10
25.7 1391925_at chemokine (C-C motif) ligand 19 (predicted) Ccl19_predicted
21.5 1369815_at chemokine (C-C motif) ligand 3 Ccl3
17.5 1367973_at chemokine (C-C motif) ligand 2 Ccl2
16.5 1379365_at chemokine (C-X-C motif) ligand 11 Cxcl11
15.2 1370832_at small inducible cytokine A4 Ccl4
6.7 1387316_at chemokine (C-X-C motif) ligand 1 Cxcl1
5.8 1369983_at chemokine (C-C motif) ligand 5 Ccl5
Chemokine receptors
55.9 1369290_at chemokine (C-C) receptor 5 Ccr5
53.5 1370083_at macrophage inflammatory protein-1 alpha receptor gene Ccr1
45.9 1393929_at chemokine (C-C motif) receptor 6 (predicted) Ccr6_predicted
41.1 1387742_at chemokine (C-C motif) receptor 2 Ccr2
11.2 1368192_at chemokine (C-X-C motif) receptor 3 Cxcr3
Regulatory or protective genes
219.364 1369764_at complement component 4 binding protein, alpha C4bpa
121.25 1387711_at interleukin 10 Il10
55.975 1368482_at B-cell leukemia/lymphoma 2 related protein A1 Bcl2a1
39.519 1371252_at suppressor of cytokine signaling 1 Socs1
39 1387835_at interleukin 1 receptor antagonist Il1rn
36.72 1387608_at indoleamine 2,3-dioxygenase Indo
28.885 1382622_at cystatin F (leukocystatin) (predicted) Cst7_predicted
23.06 1370080_at heme oxygenase (decycling) 1 Hmox1
17.922 1370113_at inhibitor of apoptosis protein 1 Birc3
16.732 1368695_at complement component 4 binding protein, beta C4bpb
8.305 1387638_a_at cytotoxic T-lymphocyte-associated protein 4 Ctla4
Immune cells related genes
229.344 1385414_at CD8 antigen, alpha chain Cd8a
144.253 1387378_at ficolin B Fcnb
103.106 1370628_at granzyme B Gzmb
67.326 1379293_at granzyme A Gzma
35.114 1393917_at CD163 antigen (predicted) Cd163_predicted
30.581 1387472_at CD3 antigen delta polypeptide Cd3d
28.319 1387739_at CD8 antigen, beta chain Cd8b
25 1370096_at perforin 1 (pore forming protein) Prf1
18.368 1370483_at CD244 natural killer cell receptor 2B4 Cd244