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Table 1 Top 50 differentially regulated genes immediately after hypoxic preconditioning

From: Analysis of the retinal gene expression profile after hypoxic preconditioning identifies candidate genes for neuroprotection

Affymetrix ID

Gene Symbol

Gene Name

FC

pVal

UPREGULATED

1440257_at

Obox6

oocyte specific homeobox 6

118.4

2.48E-07

1433837_at

8430408G22Rik

RIKEN cDNA 8430408G22 gene

35.6

6.94E-05

1424638_at

Cdkn1a

cyclin-dependent kinase inhibitor 1A (p21)

30.5

3.00E-05

1454409_at

4833408G04Rik

RIKEN cDNA 4833408G04 gene

24.0

2.07E-06

1418190_at

Pon1

paraoxonase 1

22.5

1.98E-05

1422832_at

Rgr

retinal G protein coupled receptor

22.1

6.20E-05

1454608_x_at

Ttr

transthyretin

20.1

2.67E-04

1455913_x_at

Ttr

transthyretin

20.0

3.11E-04

1458610_at

-

---

17.4

1.95E-04

1416434_at

Bcl2l10

Bcl2-like 10

17.0

2.70E-05

1444487_at

Lrat

lecithin-retinol acyltransferase

16.2

6.54E-06

1441228_at

Apold1

apolipoprotein L domain containing 1

11.7

7.21E-05

1438815_at

Hist2h2aa2

histone 2, H2aa2

10.7

1.01E-04

1416077_at

Adm

adrenomedullin

10.6

2.48E-04

1430197_a_at

Pitpnm2

phosphatidylinositol transfer protein, membrane-associated 2

10.3

5.36E-05

1428942_at

Mt2

metallothionein 2

9.7

5.12E-06

1418808_at

Rdh5

retinol dehydrogenase 5

9.7

9.82E-05

1427221_at

MGI:2143217

X transporter protein 3 similar 1 gene

9.3

1.29E-04

1430817_at

Samd7

sterile alpha motif domain containing 7

8.6

2.66E-04

1447494_at

D7Bwg0826e

DNA segment, Chr 7, Brigham & Women's Genetics 0826 expressed

7.2

5.77E-06

1428352_at

Arrdc2

arrestin domain containing 2

7.1

6.05E-05

1446587_at

-

Transcribed locus

6.9

2.32E-04

1424838_at

A330049M08Ri

RIKEN cDNA A330049M08 gene

6.8

1.21E-04

1426117_a_at

Slc19a2

solute carrier family 19 (thiamine transporter), member 2

6.8

1.80E-04

1430357_at

H3f3b

H3 histone, family 3B

6.3

5.84E-05

1422557_s_at

Mt1

metallothionein 1

6.3

5.42E-06

1454991_at

Slc7a1

solute carrier family 7 (cationic amino acid transporter, y+ system), member 1

6.1

1.39E-04

1429348_at

Sema3c

semaphorin 3C

5.9

3.55E-04

1442366_at

6820408C15Ri

RIKEN cDNA 6820408C15 gene (6820408C15Rik), mRNA

5.6

6.15E-05

1441673_at

C80120

expressed sequence C80120

5.3

1.39E-04

DOWNREGULATED

1429169_at

Rbm3

RNA binding motif protein 3

19.41

2.54E-04

1435692_at

LOC622320

similar to retinoic acid, EGF, and NGF upregulated

7.02

3.79E-05

1447363_s_at

Bub1b

budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)

6.36

8.09E-06

1416961_at

Bub1b

budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)

5.41

1.20E-06

1444172_at

-

Transcribed locus

4.72

2.64E-04

1435158_at

Rbm12b

RNA binding motif protein 12B

4.40

6.09E-05

1425083_at

Otor

otoraplin

4.03

2.21E-04

1445709_at

Mdm1

transformed mouse 3T3 cell double minute 1

3.97

1.64E-04

1450953_at

Wdr39A

WD repeat domain 39

3.70

1.93E-04

1456723_at

Prr14

Proline rich 14

3.49

2.35E-05

1456834_at

Ibrdc2

IBR domain containing 2 (Ibrdc2), mRNA

3.45

1.76E-04

1442051_at

His2h3cl

histone 2, H3c1

3.39

2.63E-04

1437647_at

Dido1

death inducer-obliterator 1

3.38

6.54E-05

1421379_at

Zfp354b

zinc finger protein 354B

3.28

3.41E-04

1424852_at

Mef2c

myocyte enhancer factor 2C

3.22

1.40E-04

1429655_at

Nudcd1

Nudcd1 NudC domain containing 1 3.19 3.84E-04

3.19

3.84E-04

1442249_at

-

Transcribed locus

3.11

1.03E-04

1416920_at

Rbm4

RNA binding motif protein 4

3.11

1.44E-04

1460107_at

1700129I04Rik

RIKEN cDNA 1700129I04 gene

3.11

1.74E-04

1453010_at

Iws1

IWS1 homolog (S. cerevisiae)

2.98

2.80E-04

  1. FC: fold change; pVal: p-value