Table 2 Differentially regulated genes with possible impact on cell survival and neuroprotection; detected and functionally clustered by DAVID.
Affymetrix ID | Gene Symbol | Gene Name | FC |
|---|---|---|---|
Up-regulated | |||
apoptosis (p ≥ 0.032) | |||
1424638_at | Cdkn1a | cyclin-dependent kinase inhibitor 1a (p21) | 30.5 |
1416434_at | Bcl2l10 | Bcl2-like 10 | 17.0 |
1442025_a_at | Zbtb16 | zinc finger and btb domain containing 16 | 3.6 |
1454109_a_at | Ptdsr | phosphatidylserine receptor | 2.4 |
1420909_at, 1451959_a_at | Vegfa | vascular endothelial growth factor a | 2.3 |
1453851_a_at | Gadd45g | growth arrest and dna-damage-inducible 45 gamma | 2.3 |
1452050_at | Camk1d | calcium/calmodulin-dependent protein kinase id | 2.1 |
1454903_at | Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | 2.0 |
cell cycle (p ≥ 0.013) | |||
1424638_at | Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 30.5 |
1416309_at | Nusap1 | nucleolar and spindle associated protein 1 | 4.4 |
1454018_at | Tlk2 | tousled-like kinase 2 (Arabidopsis) | 4.3 |
1449007_at | Btg3 | B-cell translocation gene 3 | 4.2 |
1424143_a_at, 1424144_at | Cdt1 | retroviral integration site 2 | 3.4 |
1419024_at, 1455002_at | Ptp4a1 | protein tyrosine phosphatase 4a1 | 2.7 |
1453851_a_at | Gadd45g | growth arrest and DNA-damage-inducible 45 gamma | 2.3 |
1420909_at, 1451959_a_at | Vegfa | vascular endothelial growth factor A | 2.3 |
1459978_x_at | - | gene model 877 (NCBI) | 2.0 |
1435870_at | Sycp3 | synaptonemal complex protein 3 | 2.0 |
negative regulation of transcription (p ≥ 0.031) | |||
1442025_a_at | Zbtb16 | zinc finger and btb domain containing 16 | 3.6 |
1425809_at | Fabp4 | Fatty acid binding protein 4, adipocyte (Fabp4), mRNA | 3.5 |
1425895_a_at | Id1 | inhibitor of DNA binding 1 | 3.1 |
1442397_at | Nfx1 | nuclear transcription factor, X-box binding 1 | 2.7 |
1425732_a_at | Mxi1 | Max interacting protein 1 | 2.1 |
Down-regulated | |||
regulation of transcription (p ≥ 0.09) | |||
1440343_at | Rps6ka5 | ribosomal protein S6 kinase, polypeptide 5 | 0.42 |
1450034_at | Stat1 | signal transducer and activator of transcription 1 | 0.47 |
1416826_a_at | Trfp | Trf (TATA binding protein-related factor)-proximal protein homolog (Drosophila) | 0.41 |
1450953_at | Wdr39 | WD repeat domain 39 | 0.27 |
1421379_at | Zfp354b | zinc finger protein 354B | 0.31 |
1424852_at | Mef2c | myocyte enhancer factor 2C | 0.31 |
1437647_at | Dido1 | death inducer-obliterator 1 | 0.30 |
1443952_at | Thra | thyroid hormone receptor alpha | 0.48 |
1428760_at | Snapc3 | small nuclear RNA activating complex, polypeptide 3 | 0.40 |
1456723_at | Prr14 | Proline rich 14 | 0.29 |