Figure 7
From: Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners
Peptide binding residues of 14-3-3ζ. (A) The Cβ atoms of all residues involved in binding in any of the five peptide bound structures are shown (red) along with the rest of the backbone (light blue ribbon). (B) The standard deviation in the area bound on complex formation is displayed by coloring the Cβ atoms of peptide binding residues on a gradient, from a standard deviation of 0Å2 (blue) to 10Å2 and greater (red). (C) The backbone RMSF of the 14-3-3 domain calculated over Cα atoms displayed as a color and radius gradient, from an RMSF of 0Å (blue, 0.25Å) to an RMSF of 2.0Å and greater (red, 2.0Å). (D) The side chain RMSF is displayed by coloring the Cβ atoms of peptide binding residues on a gradient, from a RMSF of 0Å (blue) to an RMSF of 0.50Å and greater (red). All parameters were calculated using all five of the peptide-14-3-3 complexes.