From: Selection of thermodynamic models for combinatorial control of multiple transcription factors in early differentiation of embryonic stem cells
(TF1, TF2) RNAP
(0, 0)
(1, 0)
(0, 1)
(1, 1)
0
1
q TF1
q TF2
w TF1TF2 q TF1 q TF2
q p
w TF1 p q TF1 q p
w TF2 p q TF2 q p
(w TF1 p + w TF2 p ) w TF1TF2 q TF1 q TF2 q p