Figure 2
From: Overlapping mouse subcongenic strains successfully separate two linked body fat QTL on distal MMU 2
QTL map for body fat traits on mouse chromosome 2. (A) Interval mapping LOD score profile for Femoral (FFP), Gonadal (GFP), Mesenteric (MFP), and Retroperitoneal (RFP) Fat Pads and the sum of all fat pads referred to as Total Fat (TF). Horizontal dashed black and gray lines represent LOD threshold value for α = 0.05 and α = 0.01 after 1000 permutations, respectively. Since each threshold differed among fat pads, only the highest thresholds are plotted. The tick marks above the x-axis represent the genotyped SNP and microsatellite markers. (B) Genotypic effects on Total Fat at the peak location of Fatq2b at 174 Mb. (C) Genotypic effects on Total Fat at 156.9 Mb. The genotypes codes are BB = b6/b6; BC = b6/cast; CC = cast/cast (D) Subcongenic strains used for the fine mapping of Fatq1 and Fatq2. Reported locations of Fatq1 and Fatq2 are displayed below the congenics (circle indicates location of the peak) [9].