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Table 2 Top 5 significant KEGG pathways identified based on the differentially regulated genes and co-regulated genes from cosine similarity analysis
| KEGG Pathways | E7fe vs. E9se | E7fm vs. E9sm | E9fe vs. E11se | E9fm vs. E11sm |
|---|---|---|---|---|
| ECM-receptor interaction | 4.94e-08 | 1.59e-03 | 5.78e-09 | 2.06e-03 |
| Focal adhesion | 3.88e-08 | 1.39e-05 | 1.32e-07 | 6.21e-04 |
| Melanogenesis | 3.34e-05 | 2.89e-02 | 2.29e-07 | 1.46e-02 |
| Calcium signaling pathway | 5.79e-03 | 5.28e-05 | 2.23e-02 | >0.05 |
| Vascular smooth muscle contraction | >0.05 | 2.30e-05 | >0.05 | 7.21e-04 |
