Skip to main content

Table 3 Differentially methylated 3 Kb regions between young and old individuals as identified by MIRA-Seq and gene expression data for annotated genes

From: Age dependent changes in the LPS induced transcriptome of bovine dermal fibroblasts occurs without major changes in the methylome

    

RNA-Seq fold difference

Fold difference*

Chr

Genomic coordinates

Gene**

Hour 0

Hour 2

Hour 8

4.6

1

72956301-72959300

XXYLT1

1.0

−1.6

−1.0

−5.3

2

25773034-25776033

SP5

1.0

1.0

1.0

3.7

2

70978934-70981933

- -

- -

- -

- -

4.7

2

126997334-127000333

ARID1A

1.0

−1.4

1.0

5

2

88469334-88472333

- -

- -

- -

- -

4.9

3

116651410-116654409

CXCR7

−1.2

−1.6

−1.3

4.9

5

117094706-117097705

- -

- -

- -

- -

4

7

52484546-52487545

- -

- -

- -

- -

−4

8

75361987-75364986

ADRA1A

1.0

1.0

1.1

4.2

8

43784287-43787286

DMRT2

−1.1

−1.3

−1.2

6.1

8

101360987-101363986

PALM2

−1.7

−2.4

−1.9

4.7

9

95637251-95640250

- -

- -

- -

- -

−4.3

11

8944985-8947984

LOC100337252

5.2

−1.6

2.5

3.7

11

95333785-95336784

- -

- -

- -

- -

−3.8

12

80725922-80728921

- -

- -

- -

- -

−6.2

17

62367994-62370993

- -

- -

- -

- -

−5.3

17

62346994-62349993

- -

- -

- -

- -

3.6

19

44563675-44566674

HDAC5

1.1

1.2

−1.5

−4.3

21

65927663-65930662

- -

- -

- -

- -

5.9

23

8944593-8947592

ANKS1A

1.3

−1.2

1.1

  1. *Data obtained by MIRA-Seq and presented as fold difference in read count of methylated regions. Positive fold change indicates higher methylation levels in cultures from younger animals while negative values are higher methylation in cultures from older animals.
  2. **DMRs with an associated gene indicate that some portion of the 3Kb region falls within an annotated gene, while - - indicates DMRs that are intergenic.
Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us