The insertion of Bov-A2 retroposon element into the TP53 P1 promoter. (A) A schematic representation of the genomic region of the TP53 P1 promoter in cow. The genomic cow chromosome 19 coordinates are indicated, based on the Baylor Btau_4.6.1/bosTau7 October 2011 assembly available in the UCSC genome browser (http://genome.ucsc.edu/cgi-bin/hgBlat?command=start). (B) The location, orientation and structure of the Bov-A2 retroposon element in the TP53 P1 promoter of Antilopinae (left) and Tragelaphini (right). Abbreviations: TSS- Transcription start site, IS1- Insertion site 1, IS2- insertion site 2.