Consistency of TM3C data with known organizational principles and KBM7 karyotype.
(a) Number of RE cut sites within reads that are fully mapped and nonmapped in the first phase mapping for KBM7 libraries. (b) Scaling of contact probability with genomic distance for three crosslinked libraries and one non-crosslinked control library. (c) Scaling of contact probability in log–log scale for three different sets of contacts identified in KBM7-TM3C-1 library. Pairwise chromosome contact matrices for (d) KBM7-TM3C-1, (e) KBM7-TM3C-4, (f) NHEK-TM3C-1 and (g) KBM7-MCcont-4 libraries. For these plots contact counts are averaged over all pairs of mappable 1 Mb windows between the two chromosomes.