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Table 5 Age-dependent mRNAs/miRNAs

From: Integromics network meta-analysis on cardiac aging offers robust multi-layer modular signatures and reveals micronome synergism

List of age-dependent miRNAs F-test (P-value < 0.05) List of age-dependent genes F-test (P-value < 0.05)
miR-106a 1810046J19RIK, 2310044G17RIK, 2900073G15RIK, ACOT1, AKR1C13,
miR-135a ALAS1, ALDOB, AMPD3, AMY1, ANKRD1, ANXA5, AOX1, APBB1, BAIAP2L1, BAX, BLCAP, C1QA, C3, CAT, CCND1, CCNDBP1, CDC37, CDC37L1, CDH22, CLU, CNOT8, COL5A2, CORIN, CP, CRHR2, CSDA, CTGF, CTSD, CXCL14, D0H4S114, D930014E17RIK, DAP, DAP3, DAZAP2, DCI, DECR1, DNAJA1, DNAJC5, DYNLL1, EDN3, EEF2, EFHD2, EIF4EBP1, FAH, FBP2, FGL2, FIGF, FXYD6, G0S2, GABARAPL1, GLUL, GP49A, GPR56, GRINA, GSTA4, GUCY1B3, H19, HADH, HDLBP, HIF1A, HIST1H1C, HIST1H2BC, HNRPDL, HOMER2, HSPA8, HSPH1, HTATIP2, HTRA1, IER3, IRAK1, ITGB6, ITM2B, IVNS1ABP, KCNK1, KLF9, LAMP1, LGALS4, LGMN, LRRC3B, LYZ2, MID1IP1, MLF1, MLYCD, MORF4L1, MRPL45, MRPL50, MXD4, MYADM, MYOM2, MYOT, NDUFA10, NDUFV1, NEDD1, NFKBIA, NNT, NT5E, OSMR, PAH, PCDHB20, PEG3, PER1, PFDN1, PGAM1, PIM3, POPDC3, POSTN, PPAP2B, PRKCQ, PRNP, PROX1, PSMB4, PTER, PTP4A3, PTTG1IP, RAB4A, RCAN1, RELA, REXO2, RFXANK, RHOU, RPA3, RPL10, RPL23, RPL37, SCARB2, SCN1B, SDPR, SEC63, SEPP1, SERPINA3N, SERPINH1, SH3GL2, SLC35A2, SLC3A2, SLC4A8, SMAD4, SNX3, SOCS3, SQSTM1, STAG2, STAP2, STAT5A, TCEA1, TCTA, TEF, TFRC, TGM2, TMSB4X, TNFAIP8, TPP1, TRPM7, TSPAN17, TSPAN4, UBA3, UNG, XPR1, YWHAE
miR-142-3p
miR-146b
miR-152
miR-199a-5p
miR-19a
miR-19b
miR-21
miR-221
miR-222
miR-223
miR-27b
miR-290-5p
miR-29a
miR-342-3p
miR-34a
miR-466d-3p
miR-374
miR-466c-5p
miR-466f-3p
miR-468
miR-574-5p
miR-677
  1. Using a linear regression model and two-tailed F-test, 24 age-dependent miRNAs and 162 age-dependent mRNAs were identified (P-value < 0.05). Bold indicates miRNAs and mRNAs included in the consensus modules. Italics indicate miRNAs with insignificant synergistic effect.
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