Figure 3

A rooted phylogenetic tree constructed with orthologs determined by orthoMCL of thirteen M. tuberculosis stains and the outgroup M. bovis BCG. The strain information is shown in Table 1. The first number in parentheses is the number of unique ortholog pairs in the strain when compared to its sister group. The second number corresponds to the differences of existing ortholog pairs in a strain when compared to its sister group. For instance, there are 60 unique ortholog pairs in KZN4207 compared with KZN605. There are 41 unique ortholog pairs in KZN605. For the ortholog pairs in both strains (groups), five more existences were detected in KZN4207 than in KZN605. The sub-groups are marked with different colors. The blue background denotes the KZN group, green denotes the H37 group, purple denotes the RGTB group and light blue denotes the CCDC group. The RGTB group was excluded from the group due to its abnormal gene counts. The number to the right of each group is the number of different ortholog pairs (unique and different) between the group and the other two groups.