Table 3 Pathway (KEGG) enrichment analysis of lost genes from three strains
From: Comparing Mycobacterium tuberculosis genomes using genome topology networks
Strain ( M. tuberculosis ) | Total Lost (vs. H37Rv) | Hits | Pathway | P-value |
|---|---|---|---|---|
RGTB327 | 599 | 17 | mtu00230:Purine metabolism | 0.00 |
12 | mtu00240:Pyrimidine metabolism | 0.01 | ||
10 | mtu00361:gamma-Hexachlorocyclohexane degradation | 0.01 | ||
13 | mtu00624:1- and 2-Methylnaphthalene degradation | 0.00 | ||
16 | mtu00632:Benzoate degradation via CoA ligation | 0.01 | ||
16 | mtu00903:Limonene and pinene degradation | 0.01 | ||
5 | mtu01053:Biosynthesis of siderophore group nonribosomal peptides | 0.01 | ||
16 | mtu02010:ABC transporters | 0.00 | ||
RGTB423 | 685 | 15 | mtu00071:Fatty acid metabolism | 0.00 |
16 | mtu00230:Purine metabolism | 0.01 | ||
10 | mtu00250:Alanine, aspartate and glutamate metabolism | 0.00 | ||
8 | mtu00260:Glycine, serine and threonine metabolism | 0.04 | ||
18 | mtu00280:Valine, leucine and isoleucine degradation | 0.00 | ||
19 | mtu00281:Geraniol degradation | 0.00 | ||
13 | mtu00330:Arginine and proline metabolism | 0.00 | ||
7 | mtu00360:Phenylalanine metabolism | 0.03 | ||
15 | mtu00380:Tryptophan metabolism | 0.00 | ||
10 | mtu00410:beta-Alanine metabolism | 0.04 | ||
6 | mtu00480:Glutathione metabolism | 0.03 | ||
13 | mtu00624:1- and 2-Methylnaphthalene degradation | 0.01 | ||
16 | mtu00632:Benzoate degradation via CoA ligation | 0.03 | ||
19 | mtu00640:Propanoate metabolism | 0.00 | ||
16 | mtu00903:Limonene and pinene degradation | 0.03 | ||
8 | mtu00910:Nitrogen metabolism | 0.01 | ||
9 | mtu00930:Caprolactam degradation | 0.04 | ||
6 | mtu01053:Biosynthesis of siderophore group nonribosomal peptides | 0.00 | ||
16 | mtu02020:Two-component system | 0.00 | ||
7 | mtu03030:DNA replication | 0.01 | ||
CDC1551 | 166 | 4 | mtu00310:Lysine degradation | 0.01 |
2 | mtu00540:Lipopolysaccharide biosynthesis | 0.03 | ||
4 | mtu00650:Butanoate metabolism | 0.02 |