TY - JOUR AU - McCallum, C. M. AU - Comai, L. AU - Greene, E. A. AU - Henikoff, S. PY - 2000 DA - 2000// TI - Targeted screening for induced mutations JO - Nat Biotechnol VL - 18 UR - https://doi.org/10.1038/74542 DO - 10.1038/74542 ID - McCallum2000 ER - TY - JOUR AU - Till, B. J. AU - Reynolds, S. H. AU - Weil, C. AU - Springer, N. AU - Burtner, C. AU - Young, K. PY - 2004 DA - 2004// TI - Discovery of induced point mutations in maize genes by TILLING JO - BMC Plant Biol VL - 4 UR - https://doi.org/10.1186/1471-2229-4-12 DO - 10.1186/1471-2229-4-12 ID - Till2004 ER - TY - JOUR AU - Till, B. J. AU - Cooper, J. AU - Tai, T. H. AU - Colowit, P. AU - Greene, E. A. AU - Henikoff, S. PY - 2007 DA - 2007// TI - Discovery of chemically induced mutations in rice by TILLING JO - BMC Plant Biol VL - 7 UR - https://doi.org/10.1186/1471-2229-7-19 DO - 10.1186/1471-2229-7-19 ID - Till2007 ER - TY - JOUR AU - Triques, K. AU - Sturbois, B. AU - Gallais, S. AU - Dalmais, M. AU - Chauvin, S. AU - Clepet, C. PY - 2007 DA - 2007// TI - Characterization of Arabidopsis thaliana mismatch specific endonucleases: application to mutation discovery by TILLING in pea JO - Plant J VL - 51 UR - https://doi.org/10.1111/j.1365-313X.2007.03201.x DO - 10.1111/j.1365-313X.2007.03201.x ID - Triques2007 ER - TY - JOUR AU - Cooper, J. L. AU - Till, B. J. AU - Laport, R. G. AU - Darlow, M. C. AU - Kleffner, J. M. AU - Jamai, A. PY - 2008 DA - 2008// TI - TILLING to detect induced mutations in soybean JO - BMC Plant Biol VL - 8 UR - https://doi.org/10.1186/1471-2229-8-9 DO - 10.1186/1471-2229-8-9 ID - Cooper2008 ER - TY - JOUR AU - Talame, V. AU - Bovina, R. AU - Sanguineti, M. C. AU - Tuberosa, R. AU - Lundqvist, U. AU - Salvi, S. PY - 2008 DA - 2008// TI - TILLMore, a resource for the discovery of chemically induced mutants in barley JO - Plant Biotechnol J VL - 6 UR - https://doi.org/10.1111/j.1467-7652.2008.00341.x DO - 10.1111/j.1467-7652.2008.00341.x ID - Talame2008 ER - TY - JOUR AU - Xin, Z. AU - Wang, M. L. AU - Barkley, N. A. AU - Burow, G. AU - Franks, C. AU - Pederson, G. PY - 2008 DA - 2008// TI - Applying genotyping (TILLING) and phenotyping analyses to elucidate gene function in a chemically induced sorghum mutant population JO - BMC Plant Biol VL - 8 UR - https://doi.org/10.1186/1471-2229-8-103 DO - 10.1186/1471-2229-8-103 ID - Xin2008 ER - TY - JOUR AU - Weil, C. F. PY - 2009 DA - 2009// TI - TILLING in grass species JO - Plant Physiol VL - 149 UR - https://doi.org/10.1104/pp.108.128785 DO - 10.1104/pp.108.128785 ID - Weil2009 ER - TY - JOUR AU - Wienholds, E. AU - Eeden, F. AU - Kosters, M. AU - Mudde, J. AU - Plasterk, R. H. AU - Cuppen, E. PY - 2003 DA - 2003// TI - Efficient target-selected mutagenesis in zebrafish JO - Genome Res VL - 13 UR - https://doi.org/10.1101/gr.1725103 DO - 10.1101/gr.1725103 ID - Wienholds2003 ER - TY - JOUR AU - Winkler, S. AU - Schwabedissen, A. AU - Backasch, D. AU - Bokel, C. AU - Seidel, C. AU - Bonisch, S. PY - 2005 DA - 2005// TI - Target-selected mutant screen by TILLING in Drosophila JO - Genome Res VL - 15 UR - https://doi.org/10.1101/gr.3721805 DO - 10.1101/gr.3721805 ID - Winkler2005 ER - TY - JOUR AU - Gilchrist, E. J. AU - O’Neil, N. J. AU - Rose, A. M. AU - Zetka, M. C. AU - Haughn, G. W. PY - 2006 DA - 2006// TI - TILLING is an effective reverse genetics technique for Caenorhabditis elegans JO - BMC Genomics VL - 7 UR - https://doi.org/10.1186/1471-2164-7-262 DO - 10.1186/1471-2164-7-262 ID - Gilchrist2006 ER - TY - JOUR AU - Smits, B. M. AU - Mudde, J. B. AU - Belt, J. AU - Verheul, M. AU - Olivier, J. AU - Homberg, J. PY - 2006 DA - 2006// TI - Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis JO - Pharmacogenet Genomics VL - 16 ID - Smits2006 ER - TY - JOUR AU - Till, B. J. AU - Zerr, T. AU - Bowers, E. AU - Greene, E. A. AU - Comai, L. AU - Henikoff, S. PY - 2006 DA - 2006// TI - High-throughput discovery of rare human nucleotide polymorphisms by Ecotilling JO - Nucleic Acids Res VL - 34 UR - https://doi.org/10.1093/nar/gkl479 DO - 10.1093/nar/gkl479 ID - Till2006 ER - TY - JOUR AU - Taniguchi, Y. AU - Takeda, S. AU - Furutani-Seiki, M. AU - Kamei, Y. AU - Todo, T. AU - Sasado, T. PY - 2006 DA - 2006// TI - Generation of medaka gene knockout models by target-selected mutagenesis JO - Genome Biol VL - 7 UR - https://doi.org/10.1186/gb-2006-7-12-r116 DO - 10.1186/gb-2006-7-12-r116 ID - Taniguchi2006 ER - TY - JOUR AU - Chen, L. AU - Hao, L. AU - Parry, M. A. AU - Phillips, A. L. AU - Hu, Y. G. PY - 2014 DA - 2014// TI - Progress in TILLING as a tool for functional genomics and improvement of crops JO - J Integr Plant Biol VL - 56 UR - https://doi.org/10.1111/jipb.12192 DO - 10.1111/jipb.12192 ID - Chen2014 ER - TY - JOUR AU - Draper, B. W. AU - McCallum, C. M. AU - Stout, J. L. AU - Slade, A. J. AU - Moens, C. B. PY - 2004 DA - 2004// TI - A high-throughput method for identifying N-ethyl-N-nitrosourea (ENU)-induced point mutations in zebrafish JO - Methods Cell Biol VL - 77 ID - Draper2004 ER - TY - JOUR AU - Henikoff, S. AU - Till, B. J. AU - Comai, L. PY - 2004 DA - 2004// TI - TILLING. Traditional mutagenesis meets functional genomics JO - Plant Physiol VL - 135 UR - https://doi.org/10.1104/pp.104.041061 DO - 10.1104/pp.104.041061 ID - Henikoff2004 ER - TY - JOUR AU - Moens, C. B. AU - Donn, T. M. AU - Wolf-Saxon, E. R. AU - Ma, T. P. PY - 2008 DA - 2008// TI - Reverse genetics in zebrafish by TILLING JO - Brief Funct Genomic Proteomic VL - 7 UR - https://doi.org/10.1093/bfgp/eln046 DO - 10.1093/bfgp/eln046 ID - Moens2008 ER - TY - JOUR AU - Colbert, T. AU - Till, B. J. AU - Tompa, R. AU - Reynolds, S. AU - Steine, M. N. AU - Yeung, A. T. PY - 2001 DA - 2001// TI - High-throughput screening for induced point mutations JO - Plant Physiol VL - 126 UR - https://doi.org/10.1104/pp.126.2.480 DO - 10.1104/pp.126.2.480 ID - Colbert2001 ER - TY - JOUR AU - Tsai, H. AU - Howell, T. AU - Nitcher, R. AU - Missirian, V. AU - Watson, B. AU - Ngo, K. J. PY - 2011 DA - 2011// TI - Discovery of rare mutations in populations: TILLING by sequencing JO - Plant Physiol VL - 156 UR - https://doi.org/10.1104/pp.110.169748 DO - 10.1104/pp.110.169748 ID - Tsai2011 ER - TY - JOUR AU - Gilchrist, E. J. AU - Sidebottom, C. H. AU - Koh, C. S. AU - Macinnes, T. AU - Sharpe, A. G. AU - Haughn, G. W. PY - 2013 DA - 2013// TI - A mutant brassica napus (Canola) population for the identification of new genetic diversity via TILLING and next generation sequencing JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0084303 DO - 10.1371/journal.pone.0084303 ID - Gilchrist2013 ER - TY - JOUR AU - Tsai, H. AU - Missirian, V. AU - Ngo, K. J. AU - Tran, R. K. AU - Chan, S. R. AU - Sundaresan, V. PY - 2013 DA - 2013// TI - Production of a high-efficiency TILLING population through polyploidization JO - Plant Physiol VL - 161 UR - https://doi.org/10.1104/pp.112.213256 DO - 10.1104/pp.112.213256 ID - Tsai2013 ER - TY - JOUR AU - Chi, X. AU - Zhang, Y. AU - Xue, Z. AU - Feng, L. AU - Liu, H. AU - Wang, F. PY - 2014 DA - 2014// TI - Discovery of rare mutations in extensively pooled DNA samples using multiple target enrichment JO - Plant Biotechnol J VL - 12 UR - https://doi.org/10.1111/pbi.12174 DO - 10.1111/pbi.12174 ID - Chi2014 ER - TY - JOUR AU - Chen-Harris, H. AU - Borucki, M. K. AU - Torres, C. AU - Slezak, T. R. AU - Allen, J. E. PY - 2013 DA - 2013// TI - Ultra-deep mutant spectrum profiling: improving sequencing accuracy using overlapping read pairs JO - BMC Genomics VL - 14 UR - https://doi.org/10.1186/1471-2164-14-96 DO - 10.1186/1471-2164-14-96 ID - Chen-Harris2013 ER - TY - JOUR AU - Stemple, D. L. PY - 2004 DA - 2004// TI - TILLING–a high-throughput harvest for functional genomics JO - Nat Rev Genet VL - 5 UR - https://doi.org/10.1038/nrg1273 DO - 10.1038/nrg1273 ID - Stemple2004 ER - TY - JOUR AU - Li, H. AU - Handsaker, B. AU - Wysoker, A. AU - Fennell, T. AU - Ruan, J. AU - Homer, N. PY - 2009 DA - 2009// TI - The sequence alignment/map format and SAMtools JO - Bioinformatics VL - 25 UR - https://doi.org/10.1093/bioinformatics/btp352 DO - 10.1093/bioinformatics/btp352 ID - Li2009 ER - TY - JOUR AU - Wittwer, C. T. AU - Reed, G. H. AU - Gundry, C. N. AU - Vandersteen, J. G. AU - Pryor, R. J. PY - 2003 DA - 2003// TI - High-resolution genotyping by amplicon melting analysis using LCGreen JO - Clin Chem VL - 49 UR - https://doi.org/10.1373/49.6.853 DO - 10.1373/49.6.853 ID - Wittwer2003 ER - TY - JOUR AU - Bush, S. M. AU - Krysan, P. J. PY - 2010 DA - 2010// TI - iTILLING: a personalized approach to the identification of induced mutations in Arabidopsis JO - Plant Physiol VL - 154 UR - https://doi.org/10.1104/pp.110.159897 DO - 10.1104/pp.110.159897 ID - Bush2010 ER - TY - JOUR AU - Bielecka, M. AU - Kaminski, F. AU - Adams, I. AU - Poulson, H. AU - Sloan, R. AU - Li, Y. AU - Larson, T. R. AU - Winzer, T. AU - Graham, I. A. PY - 2014 DA - 2014// TI - Targeted mutation of Delta12 and Delta15 desaturase genes in hemp produce major alterations in seed fatty acid composition including a high oleic hemp oil JO - Plant Biotechnol J VL - 12 UR - https://doi.org/10.1111/pbi.12167 DO - 10.1111/pbi.12167 ID - Bielecka2014 ER - TY - JOUR AU - Matsui, H. AU - Uemura, N. AU - Yamakado, H. AU - Takeda, S. AU - Takahashi, R. PY - 2014 DA - 2014// TI - Exploring the pathogenetic mechanisms underlying Parkinson’s disease in Medaka fish JO - J Parkinsons Dis VL - 4 ID - Matsui2014 ER - TY - JOUR AU - Costa, M. M. AU - Allen, C. E. AU - Higginbottom, A. AU - Ramesh, T. AU - Shaw, P. J. AU - McDermott, C. J. PY - 2014 DA - 2014// TI - A new zebrafish model produced by TILLING of SOD1-related amyotrophic lateral sclerosis replicates key features of the disease and represents a tool for in vivo therapeutic screening JO - Dis Model Mech VL - 7 UR - https://doi.org/10.1242/dmm.012013 DO - 10.1242/dmm.012013 ID - Costa2014 ER - TY - JOUR AU - Dalmais, M. AU - Antelme, S. AU - Ho-Yue-Kuang, S. AU - Wang, Y. AU - Darracq, O. AU - D’Yvoire, M. B. PY - 2013 DA - 2013// TI - A TILLING platform for functional genomics in JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0065503 DO - 10.1371/journal.pone.0065503 ID - Dalmais2013 ER - TY - JOUR AU - Dierking, E. C. AU - Bilyeu, K. D. PY - 2009 DA - 2009// TI - New sources of soybean seed meal and oil composition traits identified through TILLING JO - BMC Plant Biol VL - 9 UR - https://doi.org/10.1186/1471-2229-9-89 DO - 10.1186/1471-2229-9-89 ID - Dierking2009 ER - TY - JOUR AU - Stephenson, P. AU - Baker, D. AU - Girin, T. AU - Perez, A. AU - Amoah, S. AU - King, G. J. PY - 2010 DA - 2010// TI - A rich TILLING resource for studying gene function in Brassica rapa JO - BMC Plant Biol VL - 10 UR - https://doi.org/10.1186/1471-2229-10-62 DO - 10.1186/1471-2229-10-62 ID - Stephenson2010 ER - TY - JOUR AU - Chawade, A. AU - Sikora, P. AU - Brautigam, M. AU - Larsson, M. AU - Vivekanand, V. AU - Nakash, M. A. PY - 2010 DA - 2010// TI - Development and characterization of an oat TILLING-population and identification of mutations in lignin and beta-glucan biosynthesis genes JO - BMC Plant Biol VL - 10 UR - https://doi.org/10.1186/1471-2229-10-86 DO - 10.1186/1471-2229-10-86 ID - Chawade2010 ER - TY - JOUR AU - Greene, E. A. AU - Codomo, C. A. AU - Taylor, N. E. AU - Henikoff, J. G. AU - Till, B. J. AU - Reynolds, S. H. PY - 2003 DA - 2003// TI - Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis JO - Genetics VL - 164 ID - Greene2003 ER - TY - JOUR AU - Kuroyanagi, M. AU - Katayama, T. AU - Imai, T. AU - Yamamoto, Y. AU - Chisada, S. AU - Yoshiura, Y. PY - 2013 DA - 2013// TI - New approach for fish breeding by chemical mutagenesis: establishment of TILLING method in fugu (Takifugu rubripes) with ENU mutagenesis JO - BMC Genomics VL - 14 UR - https://doi.org/10.1186/1471-2164-14-786 DO - 10.1186/1471-2164-14-786 ID - Kuroyanagi2013 ER - TY - JOUR AU - Gonzalez, M. AU - Xu, M. AU - Esteras, C. AU - Roig, C. AU - Monforte, A. J. AU - Troadec, C. PY - 2011 DA - 2011// TI - Towards a TILLING platform for functional genomics in Piel de Sapo melons JO - BMC Res Notes VL - 4 UR - https://doi.org/10.1186/1756-0500-4-289 DO - 10.1186/1756-0500-4-289 ID - Gonzalez2011 ER - TY - JOUR AU - Uauy, C. AU - Paraiso, F. AU - Colasuonno, P. AU - Tran, R. K. AU - Tsai, H. AU - Berardi, S. PY - 2009 DA - 2009// TI - A modified TILLING approach to detect induced mutations in tetraploid and hexaploid wheat JO - BMC Plant Biol VL - 9 UR - https://doi.org/10.1186/1471-2229-9-115 DO - 10.1186/1471-2229-9-115 ID - Uauy2009 ER - TY - JOUR AU - Hwang, S. G. AU - Hwang, J. G. AU - Kim, D. S. AU - Jang, C. S. PY - 2014 DA - 2014// TI - Genome-wide DNA polymorphism and transcriptome analysis of an early-maturing rice mutant JO - Genetica VL - 142 UR - https://doi.org/10.1007/s10709-013-9755-0 DO - 10.1007/s10709-013-9755-0 ID - Hwang2014 ER - TY - JOUR AU - Dong, C. AU - Vincent, K. AU - Sharp, P. PY - 2009 DA - 2009// TI - Simultaneous mutation detection of three homoeologous genes in wheat by high resolution melting analysis and mutation surveyor JO - BMC Plant Biol VL - 9 UR - https://doi.org/10.1186/1471-2229-9-143 DO - 10.1186/1471-2229-9-143 ID - Dong2009 ER - TY - JOUR AU - Lochlainn, S. O. AU - Amoah, S. AU - Graham, N. S. AU - Alamer, K. AU - Rios, J. J. AU - Kurup, S. PY - 2011 DA - 2011// TI - High Resolution Melt (HRM) analysis is an efficient tool to genotype EMS mutants in complex crop genomes JO - Plant Methods VL - 7 UR - https://doi.org/10.1186/1746-4811-7-43 DO - 10.1186/1746-4811-7-43 ID - Lochlainn2011 ER - TY - JOUR AU - Missirian, V. AU - Comai, L. AU - Filkov, V. PY - 2011 DA - 2011// TI - Statistical mutation calling from sequenced overlapping DNA pools in TILLING experiments JO - BMC Bioinformatics VL - 12 UR - https://doi.org/10.1186/1471-2105-12-287 DO - 10.1186/1471-2105-12-287 ID - Missirian2011 ER - TY - JOUR AU - Shendure, J. AU - Ji, H. PY - 2008 DA - 2008// TI - Next-generation DNA sequencing JO - Nat Biotechnol VL - 26 UR - https://doi.org/10.1038/nbt1486 DO - 10.1038/nbt1486 ID - Shendure2008 ER - TY - JOUR AU - Biesecker, L. G. AU - Spinner, N. B. PY - 2013 DA - 2013// TI - A genomic view of mosaicism and human disease JO - Nat Rev Genet VL - 14 UR - https://doi.org/10.1038/nrg3424 DO - 10.1038/nrg3424 ID - Biesecker2013 ER - TY - JOUR AU - Hiatt, J. B. AU - Patwardhan, R. P. AU - Turner, E. H. AU - Lee, C. AU - Shendure, J. PY - 2010 DA - 2010// TI - Parallel, tag-directed assembly of locally derived short sequence reads JO - Nat Methods VL - 7 UR - https://doi.org/10.1038/nmeth.1416 DO - 10.1038/nmeth.1416 ID - Hiatt2010 ER - TY - JOUR AU - Kinde, I. AU - Wu, J. AU - Papadopoulos, N. AU - Kinzler, K. W. AU - Vogelstein, B. PY - 2011 DA - 2011// TI - Detection and quantification of rare mutations with massively parallel sequencing JO - Proc Natl Acad Sci U S A VL - 108 UR - https://doi.org/10.1073/pnas.1105422108 DO - 10.1073/pnas.1105422108 ID - Kinde2011 ER - TY - JOUR AU - Flaherty, P. AU - Natsoulis, G. AU - Muralidharan, O. AU - Winters, M. AU - Buenrostro, J. AU - Bell, J. PY - 2012 DA - 2012// TI - Ultrasensitive detection of rare mutations using next-generation targeted resequencing JO - Nucleic Acids Res VL - 40 UR - https://doi.org/10.1093/nar/gkr861 DO - 10.1093/nar/gkr861 ID - Flaherty2012 ER - TY - JOUR AU - Jabara, C. B. AU - Jones, C. D. AU - Roach, J. AU - Anderson, J. A. AU - Swanstrom, R. PY - 2011 DA - 2011// TI - Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID JO - Proc Natl Acad Sci U S A VL - 108 UR - https://doi.org/10.1073/pnas.1110064108 DO - 10.1073/pnas.1110064108 ID - Jabara2011 ER - TY - JOUR AU - Schmitt, M. W. AU - Kennedy, S. R. AU - Salk, J. J. AU - Fox, E. J. AU - Hiatt, J. B. AU - Loeb, L. A. PY - 2012 DA - 2012// TI - Detection of ultra-rare mutations by next-generation sequencing JO - Proc Natl Acad Sci U S A VL - 109 UR - https://doi.org/10.1073/pnas.1208715109 DO - 10.1073/pnas.1208715109 ID - Schmitt2012 ER - TY - STD TI - Draper BW, Moens CB. A high-throughput method for zebrafish sperm cryopreservation and in vitro fertilization. J Vis Exp. 2009; 6(29). doi:10.3791/1395. ID - ref51 ER -