Figure 4

Both positive and negative T-DMRs are more conserved than genomic background. Cumulative distribution is shown as the percentage of CpG sites under the corresponding PhastCons score in negative T-DMRs (red), positive T-DMRs (blue), all probes on the CHARM array (black, as negative control), and exons (brown, as positive control), respectively. The distribution describes the percentage of the CpG sites that have a conservation score less than or equal to a given conservation score (x-axis). Basically, the curves on the top are less conserved than those on the bottom.