Figure 2

Chromosomal rearrangements in ARR and NER. A) Representation of the position and orientation of the pair-end reads (red, green and purple arrows) supporting the deletion of a similar fragment in chromosome 3 (green bars) of ARR and NER. Positions of breakpoints (bp) and the mapping of the pair reads are shown in the reference CLE genome. White bars flanking green bars represent fragments in CLE that are deleted in ARR and/or NER. The inversion found in ARR is shown as a pink big arrow. The different elements are not drawn to scale. B) Representation of the position and orientation of the pair-end reads (represented by colored arrows) supporting several rearrangements in chromosomes 8 (gray bars) and 6 (brown bars) of NER. Positions of breakpoints (bp) and the mapping of the pair reads are shown in the reference CLE genome. Red and blue pair-ends indicate the occurrence of two consecutive but separate deletions. Green and purple pair-ends support the occurrence of both a translocation from a small fragment of one of the initially deleted stretches of chromosome 8 to chromosome 6, and a small deletion in chromosome 6. White bars flanking either gray or brown bars represent fragments in CLE that are deleted in NER. The gray bar flanking brown bars represents the fragment in CLE that was translocated from chromosome 8 to chromosome 6. The different elements are not drawn to scale.