Skip to main content

Table 2 Colon cis -eQTL that are associated with Crohn’s disease (CD) and/or ulcerative colitis (UC) as well as colorectal cancer (CRC)

From: Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci

  SNP/gene Proxy SNP* (r 2 ) eQTL p-value
Both CD and UC rs1363907/ERAP2   1.4 × 10−8
  rs6545800/ADCY3 rs2384061 (r2 = 0.82) 1.3 × 10−7
  rs4077515/INPP5E rs4266763 (r2 = 0.95) 4.7 × 10−6
  rs9858542/UBA7 rs10640 (r2 = 0.92) 8.7 × 10−6
CD only rs2549794/ERAP2   1.5 × 10−8
UC only rs9847710/SFMBT1   8.3 × 10−6
  rs6781710/NXPE1 & REX02 rs661946 (r2 = 0.94) 8.7 × 10−7
CRC rs3802842/COLCA2   1.1 × 10−6
  1. *SNPs in LD (r2 ≥ 0.8) with disease-associated GWAS SNPs from the NHGRI catalog. r2 corresponds to the correlation between the proxy SNP and the GWAS SNP, calculated based on the 48 African American samples in the colon dataset.
Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us