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Table 3 Repertoire of genes associated with type I IFN signaling pathway

From: De novo assembly and transcriptome analysis of Atlantic salmon macrophage/dendritic-like TO cells following type I IFN treatment and Salmonid alphavirus subtype-3 infection

Family Gene name Abbr Gene ID Accession no Fold increase
(TO-VS-IFN) (TO-VS-SAV3)
Co-upregulated      
 TLR Toll-like receptor 3 TLR3 Unigene9113 DAA64469 12,47 6,12
  TLR8-like precursor TLR8 Unigene2363 NP_001155165 38,85 16,52
 NLR NOD-like receptor 5 NLR5 Unigene34723 NP_001186995 23,13 20,58
 RLR Retinoic acid-inducible gene-I RIG-I Unigene7848 NP_001157171 40,77 15,32
  Melanoma differentiation associated gene 5 MDA5 Unigene6940 NP_001182108 8,41 4,87
  Laboratory of genetics and physiology 2 LGP2 CL8555.Contig1 NP_001133649 82,15 45,66
  Interferon promoter stimulating protein 1 IPS-1 Unigene12389 NP_001161824 6,07 2,95
 IRF Interferon regulatory factor 1 IRF1 Unigene15548 NP_001239293 9,68 5,04
  Interferon regulatory factor 2 IRF2 CL1885.Contig1 NP_001239280 4,00 2,97
  Interferon regulatory factor 3 IRF3 Unigene4271 ACL68544 22,38 10,30
  Interferon regulatory factor 7B IRF7B Unigene10251 NP_001165321 17,97 9,17
 JAK Tyrosine-protein kinase JAK1 JAK CL2001.Contig7 NP_571148 5,96 2,26
 STAT Signal transducer and activator of transcription 1 STAT1 CL8436.Contig1 ACT79987 8,20 3,23
  Signal transducer and activator of transcription 2 STAT2 Unigene6362 NP_001138896 6,26 3,67
 SOCS Suppressor of cytokine signaling 1 SOCS1 Unigene8629 CCC15083 114,85 116,07
  Suppressor of cytokine signaling 3 SOCS3 Unigene8797 NP_998469 6,55 3,09