Table 3 Repertoire of genes associated with type I IFN signaling pathway
Family | Gene name | Abbr | Gene ID | Accession no | Fold increase | |
|---|---|---|---|---|---|---|
(TO-VS-IFN) | (TO-VS-SAV3) | |||||
Co-upregulated | ||||||
TLR | Toll-like receptor 3 | TLR3 | Unigene9113 | DAA64469 | 12,47 | 6,12 |
TLR8-like precursor | TLR8 | Unigene2363 | NP_001155165 | 38,85 | 16,52 | |
NLR | NOD-like receptor 5 | NLR5 | Unigene34723 | NP_001186995 | 23,13 | 20,58 |
RLR | Retinoic acid-inducible gene-I | RIG-I | Unigene7848 | NP_001157171 | 40,77 | 15,32 |
Melanoma differentiation associated gene 5 | MDA5 | Unigene6940 | NP_001182108 | 8,41 | 4,87 | |
Laboratory of genetics and physiology 2 | LGP2 | CL8555.Contig1 | NP_001133649 | 82,15 | 45,66 | |
Interferon promoter stimulating protein 1 | IPS-1 | Unigene12389 | NP_001161824 | 6,07 | 2,95 | |
IRF | Interferon regulatory factor 1 | IRF1 | Unigene15548 | NP_001239293 | 9,68 | 5,04 |
Interferon regulatory factor 2 | IRF2 | CL1885.Contig1 | NP_001239280 | 4,00 | 2,97 | |
Interferon regulatory factor 3 | IRF3 | Unigene4271 | ACL68544 | 22,38 | 10,30 | |
Interferon regulatory factor 7B | IRF7B | Unigene10251 | NP_001165321 | 17,97 | 9,17 | |
JAK | Tyrosine-protein kinase JAK1 | JAK | CL2001.Contig7 | NP_571148 | 5,96 | 2,26 |
STAT | Signal transducer and activator of transcription 1 | STAT1 | CL8436.Contig1 | ACT79987 | 8,20 | 3,23 |
Signal transducer and activator of transcription 2 | STAT2 | Unigene6362 | NP_001138896 | 6,26 | 3,67 | |
SOCS | Suppressor of cytokine signaling 1 | SOCS1 | Unigene8629 | CCC15083 | 114,85 | 116,07 |
Suppressor of cytokine signaling 3 | SOCS3 | Unigene8797 | NP_998469 | 6,55 | 3,09 | |