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Table 4 Repertoire of type I IFN and SAV-3 induced antiviral genes

From: De novo assembly and transcriptome analysis of Atlantic salmon macrophage/dendritic-like TO cells following type I IFN treatment and Salmonid alphavirus subtype-3 infection

Family Gene name ABBR Gene ID Accession no Fold increase
TO-VS-IFN TO-VS-SAV3
Co-upregulated      
 TRIM Tripartite motif-containing protein 16 TRIM16 CL256.Contig2 ACI34046 14,62 5,31
  Tripartite motif-containing protein 21 (RO52) TRIM21 CL8308.Contig1 NP_001134045 19,38 8,31
  Tripartite motif-containing protein 25 TRIM25 CL9926.Contig3 ACN11344 9,30 3,73
  Tripartite motif-containing protein 39 TRIM39 Unigene7574 XP_003977898 288,01 105,42
 IFIT IFN-induced protein with tetratricopeptide repeats 1 IFIT1 Unigene6661 AAP42146 438,18 119,60
  IFN-induced protein with tetratricopeptide repeats 5 IFIT5 Unigene6169 ACI34283 76,11 52,63
 IFI IFN alpha-inducible protein 27 IFI27 Unigene6684 XP_004082421 9,22 5,00
  IFN-induced protein 44 IFI44 Unigene8623 NP_001133872 25,10 14,65
  IFN-inducible protein Gig2-like IFIGig2 CL7586.Contig1 ACH85338 73,07 28,29
 GTPase IFN-induced very large GTPase 1-like VLIG-1 CL1484.Contig1 XP_003459832 917,18 421,46
  IFN-induced GTP-binding protein Mx Mx Unigene6767 NP_001133390 147,00 56,84
 PKR dsRNA-activated protein kinase R PKR CL5598.Contig1 ABU24344 9,36 3,39
 ISG15 ISG15-like protein ISG-15 CL2919.Contig1 NM_001123640 78,80 51,16
 Viperin Viperin Viperin CL833.Contig1 NP_001134411 155,95 91,15
 Others Megalocytivirus-induced protein 1 CsMig1 CL2853.Contig4 AFR33114 18,38 13,20
  VIG-2 protein VIG-2 Unigene6370 NP_001117757 43,91 19,60
  Macrophage inflammatory protein 2 precursor MIP-2 Unigene2684 ACO13449 12,80 37,38
  Lectin galactoside-binding soluble 3-binding protein LGALS3BP Unigene6855 NP_001135263 36,76 12,21
Co-downregulated      
 EBPD Enhancer binding protein delta EBPD CL3161.Contig1 ACF94990 −2,77 −5,82
 C7-1 Complement protein component C7-1 precursor C7-1 Unigene15784 NP_001118090 −2,09 −2,18
 CXC CXC chemokine d1 CXCd1 Unigene7278 ABA86669 −2,70 −3,33
 CLEC4E C-type lectin domain family 4 member E CLEC4E CL6250.Contig1 ACI67923 −6,32 −2,22