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Table 4 Repertoire of type I IFN and SAV-3 induced antiviral genes

From: De novo assembly and transcriptome analysis of Atlantic salmon macrophage/dendritic-like TO cells following type I IFN treatment and Salmonid alphavirus subtype-3 infection

Family

Gene name

ABBR

Gene ID

Accession no

Fold increase

TO-VS-IFN

TO-VS-SAV3

Co-upregulated

     

 TRIM

Tripartite motif-containing protein 16

TRIM16

CL256.Contig2

ACI34046

14,62

5,31

 

Tripartite motif-containing protein 21 (RO52)

TRIM21

CL8308.Contig1

NP_001134045

19,38

8,31

 

Tripartite motif-containing protein 25

TRIM25

CL9926.Contig3

ACN11344

9,30

3,73

 

Tripartite motif-containing protein 39

TRIM39

Unigene7574

XP_003977898

288,01

105,42

 IFIT

IFN-induced protein with tetratricopeptide repeats 1

IFIT1

Unigene6661

AAP42146

438,18

119,60

 

IFN-induced protein with tetratricopeptide repeats 5

IFIT5

Unigene6169

ACI34283

76,11

52,63

 IFI

IFN alpha-inducible protein 27

IFI27

Unigene6684

XP_004082421

9,22

5,00

 

IFN-induced protein 44

IFI44

Unigene8623

NP_001133872

25,10

14,65

 

IFN-inducible protein Gig2-like

IFIGig2

CL7586.Contig1

ACH85338

73,07

28,29

 GTPase

IFN-induced very large GTPase 1-like

VLIG-1

CL1484.Contig1

XP_003459832

917,18

421,46

 

IFN-induced GTP-binding protein Mx

Mx

Unigene6767

NP_001133390

147,00

56,84

 PKR

dsRNA-activated protein kinase R

PKR

CL5598.Contig1

ABU24344

9,36

3,39

 ISG15

ISG15-like protein

ISG-15

CL2919.Contig1

NM_001123640

78,80

51,16

 Viperin

Viperin

Viperin

CL833.Contig1

NP_001134411

155,95

91,15

 Others

Megalocytivirus-induced protein 1

CsMig1

CL2853.Contig4

AFR33114

18,38

13,20

 

VIG-2 protein

VIG-2

Unigene6370

NP_001117757

43,91

19,60

 

Macrophage inflammatory protein 2 precursor

MIP-2

Unigene2684

ACO13449

12,80

37,38

 

Lectin galactoside-binding soluble 3-binding protein

LGALS3BP

Unigene6855

NP_001135263

36,76

12,21

Co-downregulated

     

 EBPD

Enhancer binding protein delta

EBPD

CL3161.Contig1

ACF94990

−2,77

−5,82

 C7-1

Complement protein component C7-1 precursor

C7-1

Unigene15784

NP_001118090

−2,09

−2,18

 CXC

CXC chemokine d1

CXCd1

Unigene7278

ABA86669

−2,70

−3,33

 CLEC4E

C-type lectin domain family 4 member E

CLEC4E

CL6250.Contig1

ACI67923

−6,32

−2,22