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Figure 5 | BMC Genomics

Figure 5

From: Proteome mapping of epidermal growth factor induced hepatocellular carcinomas identifies novel cell metabolism targets and mitogen activated protein kinase signalling events

Figure 5

Molecular interaction and biological pathways networks of regulated proteins in liver tumours of EGF transgenic mice. Cytoscape 3.0.2 with plugins (see Methods section) are used to generate functionally grouped network of pathways. Grouping of significant pathway terms (p ≤ 0.05) were based on kappa score threshold of 0.4, initial group size of 2 and sharing group percentage of 50. The pathway network consisted of 47 significantly regulated proteins involved in distinct pathways which are colour-coded. Note, the three individual terms are grey-coloured. Up and down-regulated proteins are coded as orange and green small discs, respectively.

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BMC Genomics

ISSN: 1471-2164

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