Functional annotation of 44 fungal Dnmt1 proteins and phylogenetic analysis of the cytosine-specific methyltransferase domain. (A) Phylogenetic analysis of 44 cytosine-specific methyltransferase domains (PTHR10629): Gray rectangles in 5B, including PF00145, PS00094, PS00095 et PR00105) from Dnmt1 fungal proteins and S. Pombe DNMT2, which was used as an outgroup. (B) Functional annotation of genes (white rectangle) with Interproscan (Cf Methods section). PTHR10629:SF10 is drawn on top of PTHR10629 (the coordinates are the same). Where PTHR10629 is not visible, it was overlapped by PF00145.