Figure 1

Gegenees analysis of genome composition of 28 genome sequences (10 Lysinibacillus , one from Lysinibacillus -related strain Bacillus sp. NRRL B-14905, and 17 from B. cereus group and B. subtilis, See Table 1 for full details). Right: heat map showing pairwise comparison of each genome pair based on similarity of fragments generated by sliding window. Plot colors reflect the similarity, ranging from low (red) to high (green). The heatmap is asymmetric because the contents of genomes differ in sizes and a similarity is calculated as a fraction of similar sequences in each genome. Left: SplitsTree dendrogram using the Nexus file exported from Gegenees. The toxic L. sphaericus strains form a single well defined tight cluster in both the heatmap and the dendogram (green square towards the top left of heatmap), and are distinct from other strains. The scale bar represents a 6% difference in average BLASTN score similarity.