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Figure 5 | BMC Genomics

Figure 5

From: Combinatorial Conflicting Homozygosity (CCH) analysis enables the rapid identification of shared genomic regions in the presence of multiple phenocopies

Figure 5

QQ plot showing lengths of runs of >20 SNPs observed when all combinations of 11 out of 17 affected family members are analysed using CCH and plotted against exponential quantiles. Arrow indicates the locus spanning the COL4A3 gene (uncorrected p = 2.5 × 10-14 given the underlying exponential distribution). CCH performed with related individuals yields an excess of longer runs compared with the analysis of the same number of unrelated individuals drawn from the HapMap Project (inset).

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BMC Genomics

ISSN: 1471-2164

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