Genome-wide expression analysis suggests a crucial role of dysregulation of matrix metalloproteinases pathway in undifferentiated thyroid carcinoma

Table 5 Validation profile for the candidate biomarker genes PTX3, COLEC12, PDGFRA and GPR110 in two independent experimental datasets

Subtype	Dataset 1 (original)	Dataset 2 (validation 1)	Dataset 3 (validation 2)
PTX3 expression profile	Original profile	Consistent	Consistent
COLEC12 expression profile	Original profile	Consistent	Consistent
PDGFRA expression profile	Original profile	Consistent	Consistent
GPR110 expression profile	Original profile	Consistent	Consistent

Validation of the Gene expression profile for PTX3, COLEC12, PDGFRA and GPR110 in two independent datasets. First column shows gene names, second column refers to the original profile as in Figure 8, third and fourth columns refer to the validation status respect to the original profile.

ISSN: 1471-2164