Genome reduction and potential metabolic complementation of the dual endosymbionts in the whitefly Bemisia tabaci

Table 4 Necessary sources for the metabolism of Portiera

Inputs	Class	Putative source	Proof
(Seleno-)Homocysteine	Amino acid	B. tabaci	[5]
Geranylgeranyl diphosphate	Isoprenoid	B. tabaci	PWY-5120
HCO₃	Anion	B. tabaci	[10]
L-Ornithine	Amino acid	B. tabaci	[20]
L-Aspartate	Amino acid	B. tabaci and Hamiltonella	ASPARTATESYN-PWY
Erythrose-4-phosphate	Sugar Phosphate	B. tabaci and Hamiltonella	NONOXIPENT-PWY
Phosphoenol-pyruvate	Carboxylic acid	B. tabaci and Hamiltonella	GLYCOLYSIS
Farnesyl-Diphosphate	Isoprenoid	B. tabaci and Hamiltonella	PWY-5123
Ribose-5-phosphate	Sugar Phosphate	B. tabaci and Hamiltonella	NONOXIPENT-PWY
Protoheme	Heme	Mitochondria	HEME-BIOSYNTHESIS-II

The sources potentially provided by Hamiltonella have been assessed from our analyses. Most of the sources not produced by the bacterial partner are classic metabolites of eukaryotes, and the corresponding biosynthetic pathways in MetaCyc are referred. Some sources do not seem to be produced by eukaryotes, but previous works on phloemophagous insects proposed that they were acquired from the host or its diet. The same assumptions have been made in this study, and the corresponding references have been indicated in the table.

ISSN: 1471-2164