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Table 5 Necessary sources for the metabolism of Hamiltonella

From: Genome reduction and potential metabolic complementation of the dual endosymbionts in the whitefly Bemisia tabaci

Metabolite Product/Pathway Putative source Proof
H2S (S2O3) (Seleno)Cysteine B. tabaci [87]
Pantothenate Co-enzyme A B. tabaci [52]
HCO3 Fatty acids, nucleic acids etc. B. tabaci [10]
Dihydroneopterin Folate B. tabaci [88]
P-Amino-Benzoate Folate B. tabaci [89]
Glucose Glucolysis B. tabaci [19]
Serine Glycine, Cysteine etc. B. tabaci SERSYN-PWY
Fe2+ Heme o, general cofactor B. tabaci [89]
Proline Glutamate B. tabaci PROSYN-PWY
E4P Pyridoxine B. tabaci NONOXIPENT-PWY
SAM Methionine B. tabaci PWY-5041
Protoporphyrin Heme o Mitochondria HEME-BIOSYNTHESIS-II
5-ES-3P Chorismate Portiera  
N-S-LL-2,6-D Lysine Portiera  
Phenyl-pyruvate Phenylalanine Portiera  
  1. The sources potentially providesssssd by Portiera have been assessed from our analyses. Most of the sources not produced by the bacterial partner are classic metabolites of eukaryotes, and the corresponding biosynthetic pathways in MetaCyc are referred. Some sources do not seem to be produced by eukaryotes, but previous works on phloemophagous insects proposed that they were acquired from the host or its diet. The same assumptions have been made in this study, and the corresponding references have been indicated in the table.
  2. Abbreviations: D-erythrose-4-phosphate (E4P); S-adenosyl methionine (SAM); 5-enolpyruvyl-shikimate-3-phosphate (5-ES-3P); N-succinyl-L,L-2,6-diaminopimelate (N-S-LL-2,6-D).
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