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Figure 4 | BMC Genomics

Figure 4

From: Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression

Figure 4

Canonical pathway categories associated with differentially methylated genes in the nonagenarians. Hypomethylation-associated genes are enriched in only three canonical pathways, thus corresponding to only a few pathway categories. Hypermethylation-associated genes are enriched in canonical pathways associated mainly with organismal and cellular growth and development. One canonical pathway can belong to several categories; for the individual pathways, see Additional file 8.

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