Table 5 Hypermethylation-specific GO process terms in nonagenarians

GO:0045935

Positive regulation of nucleobase-containing compound metabolic process

7.07E-17

2.37E-14

36

GO:0051173

Positive regulation of nitrogen compound metabolic process

1.06E-16

3.44E-14

37

GO:0031328

Positive regulation of cellular biosynthetic process

2.74E-16

8.47E-14

39

GO:0009891

Positive regulation of biosynthetic process

3.61E-16

1.06E-13

41

GO:0045893

Positive regulation of transcription, DNA-templated

5.05E-16

1.35E-13

45

GO:0019219

Regulation of nucleobase-containing compound metabolic process

7.72E-16

2.02E-13

46

GO:0010628

Positive regulation of gene expression

1.11E-15

2.78E-13

48

GO:0006357

Regulation of transcription from RNA polymerase II promoter

5.05E-15

1.15E-12

53

GO:0031326

Regulation of cellular biosynthetic process

1.07E-14

2.27E-12

57

GO:0051171

Regulation of nitrogen compound metabolic process

1.28E-14

2.66E-12

58

GO:0009889

Regulation of biosynthetic process

1.45E-14

2.96E-12

59

GO:0051254

Positive regulation of RNA metabolic process

1.8E-14

3.56E-12

61

GO:0006355

Regulation of transcription, DNA-templated

1.98E-14

3.85E-12

62

GO:1902680

Positive regulation of RNA biosynthetic process

2.06E-14

3.93E-12

63

GO:0045944

Positive regulation of transcription from RNA polymerase II promoter

2.94E-14

5.45E-12

65

GO:0010557

Positive regulation of macromolecule biosynthetic process

6.72E-14

1.19E-11

68

GO:0031323

Regulation of cellular metabolic process

1.09E-13

1.87E-11

70

GO:2001141

Regulation of RNA biosynthetic process

1.37E-13

2.29E-11

72

GO:0031325

Positive regulation of cellular metabolic process

2.22E-13

3.57E-11

75

GO:0045934

Negative regulation of nucleobase-containing compound metabolic process

2.8E-13

4.39E-11

77

GO:0031327

Negative regulation of cellular biosynthetic process

3.75E-13

5.8E-11

78

GO:0009893

Positive regulation of metabolic process

3.84E-13

5.85E-11

79

GO:0009890

Negative regulation of biosynthetic process

3.84E-13

5.78E-11

80

GO:0000122

Negative regulation of transcription from RNA polymerase II promoter

5.25E-13

7.72E-11

82

GO:0051252

Regulation of RNA metabolic process

9.69E-13

1.39E-10

84

GO:0051172

Negative regulation of nitrogen compound metabolic process

1.07E-12

1.52E-10

85

GO:2000112

Regulation of cellular macromolecule biosynthetic process

1.14E-12

1.6E-10

86

GO:0080090

Regulation of primary metabolic process

1.39E-12

1.92E-10

87

GO:0010629

Negative regulation of gene expression

2.02E-12

2.68E-10

91

GO:0010556

Regulation of macromolecule biosynthetic process

3.09E-12

3.96E-10

94

GO:0045892

Negative regulation of transcription, DNA-templated

4.17E-12

5.29E-10

95

GO:1902679

Negative regulation of RNA biosynthetic process

4.83E-12

6.07E-10

96

GO:0019222

Regulation of metabolic process

1.56E-11

1.84E-9

102

GO:0051253

Negative regulation of RNA metabolic process

1.94E-11

2.25E-9

104

GO:0010468

Regulation of gene expression

1.35E-10

1.39E-8

117

GO:0010558

Negative regulation of macromolecule biosynthetic process

1.39E-10

1.41E-8

119

GO:0010604

Positive regulation of macromolecule metabolic process

1.49E-10

1.46E-8

123

GO:2000113

Negative regulation of cellular macromolecule biosynthetic process

3.62E-10

3.38E-8

129