Table 2 Virulence genes associated with pathogenicity present in ETEC O157

Adhesins

faeG

+

+

K88 (F4) Fimbrial adhesin

fimH

+

+

Type 1 fimbriae, D-Mannose-specific adhesin

csgG

+

+

Facilitator of fibronectin-binding curli assembly

eaeH

+

+

Highly conserved adhesin

sfmA

+

+

Fimbrial-like adhesin

ecpA

+

+

E. coli common pilus

mat

+

+

mat operon

Toxins

east1

+

+

Enteroaggregative E. coli heat-stable enterotoxin

hlyA

+

+

α-Hemolysin

hlyE

+

+

Hemolysin E

eltB

+

+

Heat-labile enterotoxin B subunit

eltA

+

+

Heat-labile enterotoxin A subunit

estA

+

Heat-stable enterotoxin a

estB

+

+

Heat-stable Enterotoxin b

estB

+

Heat-stable Enterotoxin b (second allele)

Siderophores

fyuA

+

+

Iron uptake receptor

irp2

+

+

Iron repressible protein

Other

bor

+

Serum survival

traT

+

+

Surface exclusion and serum survival

fliC

+

+

Flagellin structural protein, H antigen determinant (H19 allele)