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Table 1 Comparison of genotype-specific splicing events with the overall set of alternative splicing events

From: Natural variation of gene models in Drosophila melanogaster

 

Genotype-specific splicing events

All alternative splicing events

P-value (Fisher’s exact test)

Total number of events

59

2744

 

Fraction of event types

   

Alternative donor sites

51%

46%

n/s

Alternative acceptor sites

42%

31%

n/s

Cassette exons

7%

23%

0.01

Fraction of event in UTRs

66%

29%

4.88 × 10−9

Fraction of frame-preserving events*

90%

78%

n/s

Median length of alternative gene segment (bp)*

9.5

20.5

2.2 × 10−3**

Fraction of unannotated events

75%

31%

1.45 × 10−11

  1. The percents represent fractions within the “Total number of alternative splicing events”. * – In case of alternative donor/acceptor sites, the lengths of alternative gene segments were calculated as distance between alternative splice sites. This is inapplicable for terminal alternative splicing events (i.e. alternative first you set and last exons). Thus, on the estimation of the fraction of frame-preserving splicing events and median length of alternative gene segments, we exclude splicing events with more than 500 bp between alternative splice sites. ** – p-value for Wilcoxon rank-sum test.