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Table 3 The 626 interaction hits from the ANOVA model using strain and stress as main effects, at the c threshold of q = 0.05 were uploaded on the Ingenuity Pathway Analysis database

From: Pervasive and opposing effects of Unpredictable Chronic Mild Stress (UCMS) on hippocampal gene expression in BALB/cJ and C57BL/6J mouse strains

Symbol

Entrez gene name

Affymetrix

Location

Type

Creb1

cAMP responsive element binding protein 1

1452529_a_at

Nucleus

transcription regulator

Crem

cAMP responsive element modulator

1418322_at

Nucleus

transcription regulator

Fyn

FYN oncogene related to SRC, FGR, YES

1448765_at

Plasma Membrane

kinase

Grik1

glutamate receptor, ionotropic, kainate 1

1427676_a_at

Plasma Membrane

ion channel

Homer1

homer homolog 1 (Drosophila)

1425671_at

Plasma Membrane

other

Htr1a

5-hydroxytryptamine (serotonin) receptor 1A

1450219_at

Plasma Membrane

G-protein coupled receptor

Il1b

interleukin 1, beta

1449399_a_at

Extracellular Space

cytokine

Ncam1

neural cell adhesion molecule 1

1421966_at

Plasma Membrane

other

Npy

neuropeptide Y

1419127_at

Extracellular Space

other

Ptpra

protein tyrosine phosphatase, receptor type, A

1425340_a_at

Plasma Membrane

phosphatase

Vldlr

very low density lipoprotein receptor

1417900_a_at

Plasma Membrane

transporter

  1. IPA revealed a group of 11 associated genes associated with a stress response phenotype, several of which have been previously associated with depression and depression-related phenotypes.