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Table 2 Coding consequence of the read-through isoforms

From: Functional characterization of BC039389-GATM and KLK4-KRSP1 chimeric read-through transcripts which are up-regulated in renal cell cancer

Coding consequence n % Isoforms Functional consequence
1 = exon junction in-frame 6 11.8% Predicted fusion protein ORF
2 = exon junction outside of ORF 16 31.4% 5′partner fully conserved, 3′partner fully or partially conserved OR regulatory OR NMD
3 = exon junction frameshift, premature stop codon 18 35.3% 5′partner partially conserved, 3′partner fully or partially conserved OR regulatory OR NMD
4 = exon junction with non-coding RNA 10 19.6% Encoding partner partially conserved OR regulatory OR NMD
5 = antisense transcript 1 2.0% Regulatory
TOTAL 51   
  1. The numbering in column 1 is referring to the second to last column of Table 1. NMD, Nonsense-mediated decay; ORF, open reading frame.
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