Skip to main content

Table 5 P-values of the standard and weighted association tests on the top associated SNP from the standard test for 7 quantitative traits in ARIC

From: X-inactivation informs variance-based testing for X-linked association of a quantitative trait

Trait

Top SNP

Standard

Weighted

TC

rs182215359

2.0 × 10−5

3.4 × 10−6

LDL

rs2257384

4.3 × 10−7

1.9 × 10−6

HDL

rs6530184

1.1 × 10−4

9.5 × 10−5

TG

rs5934418

7.3 × 10−6

2.4 × 10−6

SBP

rs5905825

1.2 × 10−5

1.2 × 10−5

DBP

rs7885152

2.8 × 10−6

2.6 × 10−6

BMI

rs1120140

5.7 × 10−6

3.8 × 10−6

  1. The weighed test outperformed the standard test, even though this comparison favored the standard test by using SNPs that had the smallest p-value from the standard association test for each of the seven traits.