Genome-wide investigation of mRNA lifetime determinants in Escherichia coli cells cultured at different growth rates

Table 2 Estimated coefficients and P -values of protein level models for a selection of explanatory variables

Parameter	Dependent variable: protein concentration
	μ = 0.10 h ⁻¹		μ = 0.20 h ⁻¹		μ = 0.40 h ⁻¹		μ = 0.63 h ⁻¹
	Est. Coeff	*P-value*	Est. Coeff.	*P-value*	Est. Coeff.	*P-value*	Est. Coeff.	*P-value*
Half-life	−0.14	1.7E ⁻⁰⁵	N.S		N.S		0.08	1.1E ⁻⁰²
CAI	0.48	2.4E ⁻³⁰	0.50	3.1E ⁻³⁷	0.56	2.6E ⁻⁴⁶	0.54	5.4E ⁻⁴³
Adjusted R ²	0.46		0.47		0.49		0.50

The coefficients were estimated by the minimization of least squares.
CAI: Codon adaptation index. N.S means that the parameter was not selected by the AIC algorithm. Model determinants (P-value ≤ 0.05) are displayed in bold.

ISSN: 1471-2164